摘要:

The amylase concentration in the amniotic fluid (ACAF) was studied in 138 subjects in relation to duration of pregnancy, fetal weight, L/S ratios and neonatal occurrence of respiratory distress syndrome (RDS). ACAF was found to be significantly correlated with duration of pregnancy (p < 0.001) and fetal weight (p < 0.005). The number of false immature predictions, based on a critical value of ACAF of 200 U/l, was relatively high: 36% for the gestational age ≥ 36 weeks, and 38% for fetal weight > 2,500 g. ACAF also showed a significant relationship with the L/S ratio (p < 0.0001). ACAF < 300 U/l correctly predicted all instances of L/S ratio < 2.0; however, the rate of false low predictions was 60%. In only 22 out of 138 AF samples (16%) could the performance of an L/S ratio have been avoided on the basis of the ACAF. ACAF < 300 U/l correctly predicted both cases of neonatal RDS in the study population; however, 1 of these fetuses had an ACAF of 260 U/l. There were four times as many false predictions of lung immaturity on the basis of ACAF < 300 U/l as from the L/S < 2.0.

ISSN:0378-7346    

DOI:10.1159/000299396

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

During the period from October 1, 1979 to March 31, 1981, 40 maturity tests were made on 20 pairs of twins at the Department of Obstetrics at Berlin-Neukölln Hospital. We therefore used the motor nerve conduction velocity (NCV) of the ulnar nerve combined with the Farr system. Only those children whose gestational age was absolutely certain were examined. A strong correlation emerged between the NCV level for twins and singles (r = 0.8 at p < 0.0001), so that it was possible to establish the maturity age of twins to an accuracy of ± 1 week. The levels of the NCV measurement within a pair of twins showed a high degree of agreement (r = 0.9 at p < 0.0001) in which the average fluctuation amounted to 0.5 m/s = 2–3 days. Even when there was a large variation in the weight of the twins ( > 300 gor > 15%), there were only minimal differences (r = 0.9 at p < 0.0001). On the other hand, the Farr system deviated significantly in a false-positive direction up to the 38th week of gestation. Measuring the motor NCV of the ulnar nerve proved to be a simple and precise method to assess the neonatal gestational age in twins.

ISSN:0378-7346    

DOI:10.1159/000299397

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

The relationships between experimentally induced deciduoma formation, circulating estradiol (E) and progesterone (P) levels and alterations in uterine blood flow (UBF) were studied between days 4 and 15 of pseudopregnancy (PSP: day 0 = ovulation) in rats. Blood flow was measured with an electromagnetic blood flow monitor and serum analyzed for E and P levels by radioimmunoassay. Neither uterine trauma on day 4 of PSP nor the site of trauma had any direct influence on altering UBF. A dramatic increase in UBF occurred in response to stromal proliferation on days 5–6 and continued to remain above sham-operated control levels through day 9. These vascular changes correlated temporally with the day 9 peak in uterine weight resulting from deciduoma formation. Both uterine weight and vascular fluctuations in deciduoma-bearing rats were related to the cyclic changes in E/P ratios between days 5 and 8 of PSP. A decline in UBF preceded deciduoma regression between days 9 and 15 of PSP. These results suggest that an increase in UBF is causally associated with the formation and maintenance of deciduoma in the PSP rat and that deciduoma regression may result from a subsequent decline in UBF rates. Both factors may be directly dependent on fluctuating E/P ratios.

ISSN:0378-7346    

DOI:10.1159/000299398

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

21 women who had been followed regularly during their normal pregnancies were examined in the puerperium. The relative fatty acid composition of serum lecithin was analyzed by means of gas-liquid chromatography. Palmitic acid decreased and stearic acid increased, which indicates a shift to more pathway II-synthesized lecithin in the puerperal period. Linoleic acid increased and the longer polyunsaturated fatty acids decreased. These changes were slow as compared to the changes in the saturated fatty acids. No correlations were found between the saturated fatty acids and linoleic acid dominating the polyunsaturated fatty acids. The results indicate different incorporational ways into the lecithin molecule of these fatty acid groups. It is suggested that the deacylation-reacylation cycle is responsible for the high content of longer polyunsaturated fatty acids still 1 week after delivery. 6 weeks after delivery normal values were recorded. Breast-feeding did not seem to influence the fatty acid pattern of serum lecithin.

ISSN:0378-7346    

DOI:10.1159/000299399

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

Phospholipase C (Clostridium welchii and Bacillus cereus) treatment of lactating rabbit mammary gland membranes (140,000 g pellet and sucrose density gradient purified plasma membranes) resulted in a large decrease in the binding of [3H]oxytocin to these subcellular fractions. This decrease was not due to a solubilization of oxytocin receptors but was the result of the removal of phospholipids which may participate in the hormone-receptor interaction. Phospholipase C treatment of the membrane fractions resulted in a dose-dependent removal of different classes of phospholipids. Sphingomyelin, phosphatidylcholine and phosphatidylethanolamine were removed by phospholipase C (C. welchii and B. cereus) treatment. No significant change was observed in the content of phosphatidylinositol. Phospholipase C from B. cereus reduced the content of phosphatidylserine, while the enzyme from C. welchii did not.

ISSN:0378-7346    

DOI:10.1159/000299400

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

By using a patient questionnaire, we checked the effects on sterilization of the unipolar high-frequency current method and the endocoagulation procedure in relation to late complications. In the years following high-frequency sterilization, 23 women (8.9%) were hysterectomized; in the endocoagulation group only 9 patients (2.3%) underwent hysterectomy, primarily because of the recurrence of therapy-resistant menometrorrhagia. Of those women sterilized by the unipolar HF technique, 20 (7.8%) required 1–3 postoperative curettages, whereas only 8 patients (2.1%) of the endocoagulation group required such an operation. We found that 79 patients of the HF group (30.9%) exhibited menstrual disorders compared to only 45 women (11.7%) in the endocoagulation collective. By disregarding those patients who had taken the pill or used an IUD prior to sterilization, the corrected rates for occurrence of menstrual irregularities were 22.5% for the HF group and 5.9% for the endocoagulation group, respectively.

ISSN:0378-7346    

DOI:10.1159/000299401

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299402

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283375

出版商:S. Karger AG    

年代:1902

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283376

出版商:S. Karger AG    

年代:1902

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283377

出版商:S. Karger AG    

年代:1902

数据来源: Karger