摘要:

102 pregnant women, suspected of placental insufficiency, according to their physical findings, were regularly monitored by various techniques which were related to the birth of a small-for-date infant ( < 10th weight percentile), and assessed by calculations of recognition, occurrence, and exclusion probabilities. High reliability was given by ultrasonic biometry, by human placental lactogen (HPL) and estriol both in serum, and placental perfusion measurements (113mIn) if they were within the normal range. Antepartum non-stressed cardiotocogram revealed probability rates similar to HPL in serum. Combinations of monitoring methods augmented the prognostic value, nevertheless a problem of relatively high numbers of false-positive findings remained. For large departments all methods are recommended; for smaller ones particularly antepartum cardiotocogram in combination with ultrasonic biometry is recommended.

ISSN:0378-7346    

DOI:10.1159/000299487

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

35 pregnant women (37 pregnancies) were treated with subcutaneous and/or intravenous heparin because of acute thromboembolic complications (TE) or as prophylaxis against TE. 25 pregnancies were uncomplicated. The most frequent complication was incipient premature labor, which occurred in 7 women. Other complications were retentio placentae, twin pregnancies, ablatio placentae and minor hematomas. No serious bleeding complications occurred. The treatment did not seem to affect the children.

ISSN:0378-7346    

DOI:10.1159/000299488

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

35 breech presentations at 35.8 ± 3.4 weeks of pregnancy (mean ± SD) were studied by ultrasound immediately before attempting external version. The placenta was located on the anterior wall of the uterine cavity significantly more often in the patients in which external version did not succeed and no spontaneous version occurred (48.6%) than in those in which external version succeeded or spontaneous version to cephalic presentation occurred. The relation of uterine volume to fetal dimensions in the former group was significantly more often smaller than could be expected in relation to the duration of pregnancy. The successful manipulation group included significantly more cases in which the back of the fetus was directed ventrally or dorsally from the maternal midline than did the breech presentations in which version did not occur. The birth weight was also significantly greater in the former group. Our results indicate that ultrasonic examination of the position and size of the fetus, the location of the placenta and the uterine volume is recommended before undertaking an attempt at performing external version of a breech presentation. It is sensible not to attempt this procedure, if the placenta is located on the anterior wall, if the fetus is small and if there is a small ratio between uterine volume and fetal dimensions.

ISSN:0378-7346    

DOI:10.1159/000299489

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

An unselected, consecutive series of 139 third-trimester pregnant women was investigated concerning ‘fear of delivery’. Two methods to identify women with this sentiment were used independently and on the same occasion; i.e. a personal interview and a questionnaire including statements concerning ‘fear of childbirth’ to be affirmed or denied. The results obtained by the two methods were found to correspond well, i.e. much the same women who had verbally expressed significant fear of delivery during a personal interview were also identified by means of the inventory technique. A questionnaire may therefore replace a personal interview as an instrument to conveniently accumulate a sample of pregnant, ‘anxious’ women to be further studied with regard to the possible etiology and various expressions of their ‘fear of giving birth’.

ISSN:0378-7346    

DOI:10.1159/000299490

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

84 patients with elevated serum PRL levels, ranging from 25 to 253 ng/ml, were treated with an antiserotonin agent, metergoline, at the dose of 12 mg/day for 90 days. The clinical complaint was of amenorrhea in 70 cases (plus galactorrhea in 44 cases) and of anovulation in 14 cases (plus galactorrhea in 6 cases). Hyperprolactinemia was due to a pituitary adenoma in 18 cases; in 53 cases it was of unknown origin, while in 7 cases it followed treatment with neuroleptics or with oral contraceptives and in 6 cases it followed a puerperium. In patients with amenorrhea, metergoline induced the appearance of menses in 61 cases (94 %), and of ovulation in 46 cases (82 %). In 13 of the 14 patients with anovulation, ovulation was restored. Galactorrhea disappeared in 40 out of 50 patients. Metergoline normalized serum PRL levels ( < 20 ng/ml) in 46 cases and significantly reduced serum PRL levels in all but 3 of the remaining patients. In spite of suggested nonhormonal contraceptive measures, 14 patients became pregnant; 2 had abortions and the remaining 12 patients completed by vaginal delivery, uneventful pregnancies. These results indicate metergoline as a safe and effective drug in the management of hyperprolactinemic amenorrhea and anovulation. 49 patients were followed for 2 additional months, receiving no treatment (24 cases) or metergoline at a reduced daily dosage (8 mg/day, 25 cases). Within 60 days, 60% of the first group had relapse of the clinical condition and a rebound elevation of serum PRL levels while only 20% of the second group experienced relapse of amenorrhea and rebound elevation of serum PRL levels (p < 0.01).

ISSN:0378-7346    

DOI:10.1159/000299491

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Norethisterone acetate (NET), levonorgestrel (NORG) and medroxyprogesterone acetate (MPA) were administered to oophorectomized women to evaluate the effects on individual serum phospholipids as well as serum lecithin and cholesterol ester fatty acid composition. Blood samples were drawn after a 3-week period without hormonal replacement therapy and after 3 weeks on each progestogen. NORG reduced cephaline and lecithin with a concomitant increase in lysolecithin. This shift in individual phospholipids has previously been induced by exogenous androgens. The 17C-alkylated synthetic progestogens NET and NORG but not the non-alkylated MPA caused a redistribution among the 1 -position fatty acids of serum lecithin with an increase in palmitic concomitant with a decrease in stearic acid. These findings indicate differences between 19-nortestosterone derivatives and 17-hydroxyprogesterone derivatives in effect on individual serum phospholipids and in influence on liver lecithin synthesis as judged from serum lecithin fatty acid composition.

ISSN:0378-7346    

DOI:10.1159/000299492

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299493

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283094

出版商:S. Karger AG    

年代:1901

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000315252

出版商:S. Karger AG    

年代:1901

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283095

出版商:S. Karger AG    

年代:1901

数据来源: Karger