ISSN:0265-9247    

DOI:10.1002/bies.950010103

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

ISSN:0265-9247    

DOI:10.1002/bies.950010104

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractNew methods of marking cells enable single clones to be followed during embryonic development. They can be used for the construction of fate maps and for the investigation of induction and determination.

ISSN:0265-9247    

DOI:10.1002/bies.950010105

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractUteroferrin, a purple‐colored, iron‐containing acid phosphatase, with many of the properties of a lysosomal hydrolase, transports iron from the mother to the conceptus in pregnant pigs. Uteroferrin, however, is but one member of what may be a broad class of iron‐containing phosphatases with unusual spectral properties which result from a novel type of di‐iron active site. The biological function of uteroferrin is unknown. We argue here that the in vivo function of uteroferrin, despite its undoubted ability to act as a potent acid phosphatase, is that of a transplacental iron tran

ISSN:0265-9247    

DOI:10.1002/bies.950010106

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractThe introduction of recombinant DNA technology into the field of genetics has led to a rapid advancement of our knowledge of genes and genome structure. Such technology, applied to the human genome, has provided valuable information concerning the nature and possible treatment of inherited disorders. The possibility that this knowledge will pave the way for the correction of at least some of these disorders has captured the imagination of the informed public. In this review we look at the accomplishments of molecular pathologists to date and how new techniques are being applied to the study of inherited disease.

ISSN:0265-9247    

DOI:10.1002/bies.950010107

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractPolypeptide growth factors (mitogens) which stimulate proliferation of fibroblasts and epithelial cells also rapidly activate transmembrane ion transport systems. The mitogen‐induced Na+influx is due to the activation of a Na+/H+antiport. Recent methodological developments allow, for the first time, precise measurements of the factors that control activation of the Na+/H+antiport by these agents, and provide the tools needed to assess the physiological significance of this exchange mechanis

ISSN:0265-9247    

DOI:10.1002/bies.950010108

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractHigher plant nuclear genomes contain many families of dispersed repeats that change during evolution. Recent evidence from studies on genetically defined transposable elements raises the possibility that many of the dispersed repeats are remnants of such elements. Transposition of DNA has also occurred between mitochondria, chloroplasts and nuclei, a fact that underlines the major role played by DNA transposition in determining the structure of plant genomes.

ISSN:0265-9247    

DOI:10.1002/bies.950010109

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractThe cloning of eukaryotic genes by standard recombinant DNA techniques permits their structural characterization. However, analysis of the expression properties of these genes often requires their introduction into and replication within eukaryotic cells in culture. Certain viral vectors based on the papilloma viruses may prove to be especially important in such investigations. These ‘shuttle vectors’, capable of replication in both bacterial and eukaryotic cells, have already provided several findings of interest about the relationship between eukaryotic gene structure and function. Further analysis of these vectors and their properties promises to enhance their use as investigative to

ISSN:0265-9247    

DOI:10.1002/bies.950010110

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

ISSN:0265-9247    

DOI:10.1002/bies.950010111

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

ISSN:0265-9247    

DOI:10.1002/bies.950010112

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY