ISSN:0254-4962    

DOI:10.1159/000284950

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284951

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284893

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

The interrelationships between the various symptoms of schizophrenia may be explored by examining their intercorrelations. Five different factor analytic studies, which examine these interrelationships, are summarized. Three major factors emerge consistently: psychotic, disorganized, and negative. These three factors appear to represent three dimensions of the psychopathology of schizophrenia.

ISSN:0254-4962    

DOI:10.1159/000284894

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284952

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284954

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

Negative symptoms (and cognitive impairments) in schizophrenia are a correlate of early onset and poor outcome. It is plausible that they are related to an arrest of brain development, for which there is now considerable evidence, but the precise relationship is elusive. In one post-mortem study negative symptoms were related to a reduction in brain length and in an MRI study to an asymmetry of sulcal CSF. It is proposed that the phenomena of psychosis (including negative symptoms) can be understood as part of the diversity of human personality structure generated by a process of sexual selection acting on a sexual dimorphism for cerebral asymmetry.

ISSN:0254-4962    

DOI:10.1159/000284895

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284955

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

Schizophrenic psychopathology is heterogeneous and multidimensional. One of the more fruitful strategies to investigate more homogenous domains of psychopathology has been the positive-negative syndrome approach. However, this approach is unable to address a number of important issues. Most schizophrenics present a mixed syndrome; the criteria for what constitutes a positive and negative syndrome are variable; distinguishing primary from secondary negative symptoms can be difficult. In order to address some of these problems, we propose the introduction of a 5-syndrome model based on a reanalysis of factor-analytic procedures used on 240 schizophrenics assessed with the Positive and Negative Syndrome Scale: A negative, positive, excitement, cognitive and depression/anxiety factor. This 5-factor solution is supported by 4 independent and comparable factor analyses. Data on internal consistency of the 5 factors and on initial validation using demographic and clinical variables are presented.

ISSN:0254-4962    

DOI:10.1159/000284896

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284956

出版商:S. Karger AG    

年代:1995

数据来源: Karger