摘要:

This study was conducted to determine whether the patterning of EEG and somatosensory evoked response (SER) variables, as determined by the correlations between them, differs with respect to psychiatric diagnosis. Subjects were 43 nonpatients and 90 psychiatric inpatients. SER modified recovery function recordings provided 36 variables, reflecting amplitude and its variations with different stimulus conditions. A 10-min left parietal EEG was quantitatively analyzed to give mean amplitude and frequency and variability measures. Correlations between EEG and ER variables were compared both for unmatched groups of nonpatients, schizophrenics, psychotic depressions, and nonpsychotics and for smaller age and sex-matched diagnostic groups. The results revealed a number of correlation differences between clinical groups. The nature of the differences suggested diagnostic specificity for EEG-ER patterning, which may provide a new, psychiatrically relevant electrophysiological variable.

ISSN:0302-282X    

DOI:10.1159/000117470

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Previous results from our laboratory support the hypothesis that measurements of EEG mean integrated amplitude (MIA) are correlated with the depth of depression as assessed by a rating scale, and also with the degree of memory impairment during depression. Moreover, it could be shown that there occurs, during severe depression, a more pronounced involvement of the dominant (DH) than of the non-dominant (NDH) brain hemisphere. A similar interhemispheric difference has also been found in a previous study of visual averaged evoked responses (V.AER).

ISSN:0302-282X    

DOI:10.1159/000117471

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The effects of benserazide on the level of homovanillic acid and 5-hydroxy-indoleacetic acid in CSF have been investigated in 1 manic and 11 depressed patients. Benserazide induced no change on both metabolites. This negative result supports the view that monoamine metabolites in CSF, in the absence of loading with an exogenous precursor, originate mostly from brain parenchyma, without significant contribution of the metabolism in capillary walls.

ISSN:0302-282X    

DOI:10.1159/000117472

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The relation between initial clinical symptomatology and long-term course of illness appears to be reliable. Prognostic models, as well as an eyperienced physician, can predict long-term risk of schizophrenic defects from a few items.The prognostic models also seem to be valid for international comparisons of prognosis. The improved prognosis of schizophrenia over the last 30 years is ascertained. The series of about 4,500 cases provides a sufficiently large number of patients for the analyses of well-defined subgroups. This has been done especially for schizophrenia, using the Leonhard classification.

ISSN:0302-282X    

DOI:10.1159/000117473

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

After a mean test-retest period of 16 years a sample of 39 initially chronic as well as acute/subacute schizophrenic patients showed a statistically significant normalization of associative performance. This finding was corroborated by a cross-sectional comparison between the same 39 patients and a sample of chronic schizophrenics (n = 261) tested 16 years ago. The findings were attributed to effects of psychotropic drugs and improved psychiatric treatment.

ISSN:0302-282X    

DOI:10.1159/000117474

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

148 chronic schizophrenics admitted between 1938 and 1961 had previously been followed up. In 1972, they were re-examined, on the average 10 years after the first follow-up. 44 belonged to a series of patients studied between 1955 and 1957 with a battery of conditional reflex tests. The patients belonging to the experimental series were retested with word associations. From an experimental point of view the patients performed better over the prolonged observation period. The clinical state also showed improvement. A comparison of the chronic hospital population during 1955–57 and 1972–74 suggests that the new chronics present much less of the severe schizophrenic deterioration than the old ones. They also have remarkably better verbal functions. These changes are assumed to be mainly due to drug treatment. The beneficial effects of drugs appear to come mainly within the first 2 ye

ISSN:0302-282X    

DOI:10.1159/000117475

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The use of strict criteria for the diagnosis of schizophrenia is quite predictive of a bad prognosis. Should the patient not meet such strict criteria, a family history of remitting illness may be helpful in suggesting a better outcome. In this latter group, the subtype diagnosis of catatonic schizophrenic carries with it a better prognosis.

ISSN:0302-282X    

DOI:10.1159/000117476

出版商:S. Karger AG    

年代:1975

数据来源: Karger