ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04567.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04568.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04569.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04570.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04571.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACT:Three hundred seventy‐two Chinese patients with atopic dermatitis were compared with a Caucasian population for the basic features. Significant findings occurred: personal or family history of atopy, early age of onset, xerosis, ichthyosis, palmar hyperlinearity, and facial pallor. Laboratory findings of immunologic alteration and altered pharmacologic reactivity are relatively more important feature for the diagnosis of atopic dermatiti

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04572.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACT:The metabolism of L‐tryptophan (TRP) before and after an oral loading dose of 20 mg/Kg body weight was studied in three patients with actinic reticuloid (AR) and four healthy male volunteers. The preload mean plasma TRP concentrations and mean 24‐hour urinary excretions of TRP in the AR group were significantly lower than in the control group. After oral TRP administration, plasma TRP concentrations increased normally in AR, thereby excluding defective intestinal absorption. The mean preload and postload excretions of kynurenic acid (KA), xanthurenic acid (XA), 5‐hydroxyindoleacetic acid (5HIAA), and 3‐indoleacetic acid (3IAA) were not significantly different between the two groups. We conclude that KA, which has been shown to have phototoxic properties in vitro, is not altered primarily in AR, and that the reported abnormalities of TRP metabolism are most tikely the consequence of the severe photosensitivity in this d

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04573.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACT:A patient with malignant pyoderma brought into complete remission with immunosuppressive cyclophosphamide treatment after the failure of multiple other therapies is reported. The entity of malignant pyoderma with its clinical characteristics, laboratory and biopsy findings, complications, and modalities of therapy is reviewed.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04574.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACT:There is a yearly outbreak of endemic leg ulcers in Thailand Corynebacterium pyogenes, a pathogen to animals, is frequently isolated from the fresh lesions in addition to common pyogenic bacteria such as beta‐hemolytic streptococci mostly group A, and Staphylococcus aureus and Staphylococcus epidermidis. Although circulating titers of IgG and IgM anti‐C. pyogenes antibodies were found to be very low in studied cases, intradermal skin test with C. pyogenes vaccine containing nonviable 105microorganisms induced an erythematous reaction with maximum intensity at 6 hours; direct immunofluorescence showed granular deposition of C3 along the dermoepidermal junction at this time. Unexpectedly, the sites of such a skin test that subsequently underwent biopsy presented tender erythematous induration 1 week later and developed granulomatous ulceralive lesions after 10 days in 11 of 15 patients.Radioimmunoassay for C5a and C5a of arginine demonstrated that C. pyogenes activaited complement even in the absence of specific antibodies. These findings suggest the importance of skin injury followed by infection with C. pyogenes in the development of endemic leg ulcers supporting our hypothesis that the infection of accidentally traumatized skin by C. pyogenes, which is carried by Oriental‐eye files, induces the granulomatous lesions of endemic leg u

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04575.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1987.tb04576.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY