摘要:

Chemicals used on fabrics to improve 10 different performance characteristics have resulted in irritant or allergic contact dermatitis. The most significant problem is due to formaldehyde and N‐methylol compounds to produce durable press fabrics. Little is known about incidence of finish dermatitis or mode and amount of transfer of chemicals from fabric to ski

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01145.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Hospital cleaning personnel were examined for occupational dermatoses. 356 persons were included in the study. The UJJC ranged from 20 to 63 years with a mean of 40.1 years. The period prevalence rate of moderate and severe eczema was 12% (10% in men and 19% in women). In 88%, the eczema was of a duration longer than 2 years. Positive patch tests were found in 10% of men and 53% of women with eczema. The main allergens were nickel, cobalt, chromate and rubber chemicals. Positive tests to cleaning agents were rare. One case of contact allergy to sodium dichloroisocyanurate and one to lysol were, diagnosed. Irritant factors played: a major role in most cases (92%). Fungus infection as a cause or complication in hand eczema should not be left out of consideration: in 2 persons, a mycosis of hands and or fingernails was diagnosed.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01146.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

The number and nature of allergic occupational glove dermatoses were analysed. 542 cases of allergic contact dermatosis were diagnosed during 1974–1983. Amongst these, 68 (12.5%) were caused by rubber or plastic gloves. 2 patients had contact urticaria due to rubber gloves.Gloves were the main cause of occupational allergic rubber eczema, inducing 63 (58.3%) of 108 rubber eczema cases. 38 of them had positive reactions to rubber chemicals and glove material. 14 to glove material only, and 11 to rubber chemicals. 5 cases of allergic eczema from plastic gloves were diagnosed, all due to polyvinyl chloride (PVC). 2 cases of contact urticaria from natural rubber gloves were diagnosed by a provocation test. Epicutaneous testing with material of natural rubber gloves and rubber chemicals was negative.The present study shows that allergy to rubber gloves is usual, while allergy to plastic gloves is rare. Thus, plastic gloves should be used, when possible. Patch testing with protective gloves should always be used when patients develop prolonged hand dermatitis and where the possibility of glove eczema exist

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01147.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Previous studies in humans and guinea pigs indicate that Langerhans cells (LC) participate in elicitation of allergic contact dermatitis. The number and morphology of LC was determined in acute and healed allergic patch test sties, control (petrolatum) sites and normal skin in nickel‐sensitive individuals using OKT6 monoclonal antibody and avidin‐biotin/peroxidase labeling. Compared to normal skin, the staining intensity and number of epidermal LC was significantly increased in allergic (p<0.02) and petrolatum control (p<0.02) sites, and in 6‐ to 8‐week old allergic patch test sites (p<0.006). The in situ changes in LC induced by petrolatum alone may be a result of the occlusive patch test, or may suggest that petrolatum is not as neutral as previously believed. The nickel‐induced increase in LC may indicate changes in the LC present in the epithelium at the time of testing, or migration of additional LC into the epithelium, which can then remain in situ for weeks after the antigenic challenge. The specificity of the LC increase in allergic contact dermatitis is questioned on the basis of the increase noted with p

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01148.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

The sensitizing capacities of 2‐methylol phenol (2‐MP), 4‐methylol phenol (4‐MP) and 2,4,6‐inmethylol phenol (2,4,6‐MP) were investigated with the guinea pig maximization test. These compounds are known sensitizers in phenol‐formaldehyde resins. The study was performed in order to assess and compare the degree of the sensitizing capacities of these chemically related substances. The animals were also rechallenged with the sensitizer and 5 chemically related compounds in order to study the cross‐reaction patterns.2‐MP Was demonstrated to be a strong sensitizer, 4‐MP a moderate sensitizer and 2,4,6‐MP a weak sensitizer. With 2‐MP as the sensitizer, o‐cresol and 2,4‐dimethyl phenol were possible cross‐reacting substances, p‐cresol and 2.4‐dimethylol phenol were possible cross‐reacting compounds for 4‐MP.The chemical investigation by high pressure liquid chromatography indicated that the com

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01149.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

The dermatitic constituents of the glandular hairs of plants in the family Hydrophyllaceae comprise a class of uncommon natural products called “phacelioids”. The chemical structures consist of various elaborations of hydroquinone attached to a C10to C20prenyl chain. Certain of these compounds are equivalent to the urushiols ofToxicadendron (Rhus)in their capacity to sensitize humans. Although structurally related to the urushiols, the phacelioids do not appear to cross‐react in humans either with urushiol, or between phacelioids with different prenyl c

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01150.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

7 patients who reacted on patch testing to medicaments, but who had negative reactions to the individual ingredients are described. The possible mechanisms of this phenomenon are discussed.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01151.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

4 workers developed hand dermatitis in an automated starch modification process plant. 2,3‐epoxypropyl trimethyl ammonium chloride (EPTMAC), a quaternary ammonium compound used as a cationizing chemical, produced allergic reactions in all 4 patients. They had only been in contact with EPTMAC for a shore time before developing dermatitis, which indicates that EPTMAC is a strong sensitizer.Immunohistochemistry and electron microscopy showed the Features or an allergic patch test. An industrial hygiene project was initiated at the factory to prevent new eases. It revealed many risks of skin contact with the process chemicals. Thus an automated process does not guarantee protectio

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01152.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Musk ambrette has become one of the commonest photosensitizers in many countries and is the cause of persistent light reactions in many patients. A simple method is presented for qualitative analysis for musk ambrette and other nitromusks in colognes using thin‐layer chromatography with toluene as carrier solvent and visualization under UVL. It is useful for identifying such colognes so colognes so that proper recommendations can be given to patients sensitive to musk ambrette. 14 of 32 men's colognes, analysed by TLC und confirmed on GCMS, were found to contain musk ambrette, the concentration varying from 0.02 to 0.59% w/

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01153.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Among patients with a history of metal sensitivity, 50 were patch‐test‐negative to nickel, cobalt and chromate. 20 of them were further examined epicutaneously and intracutaneously. They were also studied with a clinical diagnostic method for symptoms and signs of atopy. Most patients in this category were found to be ato

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01154.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY