摘要:

Predictive tests are of value in forecasting the response of a population to a sensitizer; diagnostic testing is used to determine what substances may actually be producing dermatologic problems. Skin sensitization predictive and diagnostic data for the eleven most frequently encountered skin sensitizers in Western Europe, Canada and the United States are reviewed. These compounds include two drugs (benzocaine and neomycin), two cosmetic ingredients (p‐phenylenediamine and balsam of Peru), four preservatives (formaldehyde, ethylenediamine, parabens and mercurials) and three ingredients of wearing apparel (nickel, chromium and thiram). Many of the data were collected by the North American Contact Dermatitis Group and the International Contact Dermatitis Research Group on tests with 1,200 and 4,825 dermatologic patients, respectively; the remainder were obtained by individual investigators with smaller groups of subjects. The data obtained by various investigators are discussed in relation 10 the factors which affect the extent and degree of sensitization which they can caus

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02972.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Industrial rehabilitation is identified as an integral part of the process of patient resettlement. The organization of the Government‐sponsored Employment Rehabilitation Service is described. The low incidence of dermatitis as seen by medical advisers in that Service is explained. Ways in which employment medical advisers can provide complementary support to consultant dermatologists is suggeste

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02973.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

The frequency of positive patch tests to 13 rubber accelerators in Poland was recorded. Of particular interest was the relatively large group of patients positive to several, mostly chemically unrelated, accelerators. The mechanism of this multiple sensitivity is discussed. Positive tests to N‐isopropyl‐N‐phenyl‐p‐phenylenediamine were observed in more than half of the patients reacting to several aromatic amines. Anamnesis indicated that in the ease of cross‐reactions to many aromatic amines, none of the patients positive to N‐isopropyl‐N‐phenyl‐p‐phenylenediamine had complained of a reacti

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02974.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

The preparation of food in restaurant kitchens carries a high risk of occupational dermatoses. Analysis of 33 cases revealed four different etiological types. Simple irritant dermatitis was rare (2 cases), plain contact dermatitis was more common (6 cases). Fifteen patients had relevant patch tests and scratch tests; ten had positive scratch tests only to explain the cause of their dermatitis. The last type was termed protein contact dermatitis. The major type IV allergens incriminated were metals, onion and garlic. The major proteinaceous allergens indicated by history and test results were fish and shell‐fish. Open patch tests with the incriminated foods may cause erythema or oedema on normal skin after 20 minutes. Previously eczematous, now normal looking, skin often responds with a crop of dyshidrotic vesicles preceded by erythema and itching 30 minutes after the application of an open test. Examination for specific IgE is not always positive in such cases. Inhalant allergy was rare. The results indicate that food handlers are sensitized by the protein they touch, and then react to later contact with the proteins. Protein contact dermatitis is similarly common among veterinary surgeons, while the importance in other occupational groups remains to be studie

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02975.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

The prevention of allergic complications depends on the use of topical medications which have proved to be rare sensitizers. This is particularly true for stasis ulcers and eczemas which are notoriously readily sensitized. Topical erythromycin has proved in be such a non‐sensitizing topical antibiotic. In a series of 60 patients with stasis ulcers, erythromycin in the form of llotycin ointment (erythromycin in petrolatum) was applied. Not a single instance of allergic sensitization occurred. No instances of sensitization with positive patch tests to topical erythromycin have been reported. Maximization tests with topical erythromycin did not produce sensitization. Topical erythromycin. an effective antibiotic, should be substituted for neomycin which is a common sensitize

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02976.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02977.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02978.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02979.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02980.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1976.tb02981.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY