摘要:

The purpose of the present investigation was to study the sequential stages in the development of a periodontal lesion starting from a healthy periodontium. Twenty inbred Beagle dogs 10 months of age and weighing 10–12 kilos were used. The animals were equally divided into one experimental and one control group. Throughout the experiment all dogs were given a diet containing 400 gm pellets and 25 gm soya flower. From day zero the teeth (in the left jaws) of the control dogs were twice dally subjected to a careful but gentle brushing with tooth brush and dentifrice. The teeth of the experimental group animals were not cleaned. The dogs were examined at regular intervals during an 18 month period.The results show that it is possible in young dogs to induce gingivitis which gradually develops into periodontitis simply by allowing plaque to accumulate on teeth. The cleaned teeth did not show signs of gingivitis or periodontitis during the entire experiment. It is proposed that in the Beagle dog the progression of the lesion during an 18 month period may occur in three stages: I) subclinical gingivitis, II) clinical gingivitis and III) periodontal breakdown. Subclinical gingivitis was characterized by a rapidly increasing gingival exudation and migration of crevicular leukocytes, i. e. signs off acute inflammation. Clinical gingivitis was characterized by changes in gingival colour, texture and bleeding tendency but only minor alterations of the number of crevicular leukocytes. Periodontal breakdown, characterized by loss of subgingival fiber attachment, occurred only in areas of clinical gingiviti

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb00735.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02156.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02157.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

The binding of chlorhexidine to proteinsin vitrohas been shown to involve albumin in both serum and saliva. The binding, which is pH‐ and concentration‐dependent, occurs both to proteins remaining in solution and to proteins precipitated during the reaction. Both reactions are reversible, although that to precipitated protein apparently involves a stronger binding. If the latter can be correlated to thein vivosituation, it is suggested as a possible explanation of the extended retention of chlorhexidine in the mouth despite the rather rapid turnover of sal

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02158.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02179.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02180.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02181.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

The uptake of chlorhexidine to hydroxyapatite was studiedin vitro.Data were obtained indicating a multilayer adsorption at high concentration (>0.02 %) and a stable monolayer at lower concentrations. The clinical significance of such a monolayer in plaque prevention is discussed. Adorption of chlorhexidine did not affect the acid solubility of hydroxyapatite.

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02159.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02174.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1973.tb02182.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY