摘要:

Three phases of lichenoid reactions are defined: 1) the primary phase, 2) the established phase; and 3) the senescent phase. Lichen striatus is characterized by a primary pattern that may be apparent in the epidermis, the hair follicles, and rarely the sweat glands and ducts. Focal areas of established lichenoid reaction, that are indistinguishable from lichen planus, are common. They usually are confined to the tips of elongated rete ridges. Established lichenoid patterns are occasionally present in hair follicles and are indistinguishable from those seen in lichen planopilaris. Eccrine hidradenitis, a feature of lichen striatus, is rarely seen in lichen planus. Lichen planus may be an adaptive epidermal response to a clone of aggressive lymphocytes and, as such, may be a manifestation of auto‐immunity. In lichen striatus, senescent lichenoid patterns resemble those seen in lichen nitidu

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00825.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Forty‐seven biopsies of pustules from patients with recalcitrant pustular eruptions of the palms and soles were examined blind and the results were subsequently compared among three clinical sub‐groups: acrodermatitis continua, pustular psoriasis and pustulosis palmaris et plantaris. With the exception of three cases, it was not possible to make a diagnosis of psoriasis on the basis of histology alone. Histological findings were otherwise uniform and typical: intra‐epidermal, unilocular, well‐delineated pustules. No significant differences were found among the three subgroups. In view of the uniform histology, the unknown etiology and the uncertain clinical classification, the authors prefer the clearly descriptive term pustulosis palmaris et pl

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00826.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A 19‐year‐old Moroccan male was found to have total absence of serum alpha1‐antitrypsin, a major inhibitor of elastase. This patient had chronic obstructive lung disease, hyperextensibility of the skin over the cheeks and wrists, and hyperlaxity of the hand joints. Microscopic sections of the skin revealed a thickened dermis with shortened and rarefied clastic fibers. Ultrastructural study showed collagen fibers with variable and irregular diameters. Elastic fibers were scarce and their relatively poor matrix was surrounded by numerous microfibrils. The outline of the fibers was irregular with deep recesses filled with microfibrils. The ergastoplasm of the fibroblasts was well developed. The differential diagnosis with other connective dystrophies showed the original characteristic of this case. Clinically and histopathologically, the skin abnormalities are probably related to the deficiency in elastase inhi

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00827.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

The ultrastructural changes in seven cases of lichen selerosus et atrophicus are described. An interesting epidermal alteration was the presence of collagen fibrils in the intercellular space; furthermore, the basal cells were altered by condensation and homogenization of the tonofibrils. The basement membrane was not uniform and often multilayered. The anchoring fibrils were numerous. In the cutis intertwining strands of fine filaments, bundles of immature collagen and normal collagen could be found. In lichen sclerosus et atrophicus the dermo‐epidermal interrelationship is disturbe

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00828.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Interaction between connective tissue cells and hair growth in the rat has been studied by radioautography afterin vivoandin vitropulse labelling with thymidine, uridine, histidine, leucine and proline. The connective tissue, which surrounds and integrates the hair bulbs as a unit, contains cells of various types which have a cyclic metabolic activity. This cyclic activity is coordinated with the hair growth cycle. The number of nuclei which actively synthesize DNA in the dermal cells, mainly those of endothelial and migratory cells, significantly increases during the short and transient anagen 4 substage. RNA and protein synthesizing activities are also present in all cell types and seem modulated by the hair cycle although to a lesser degree. This data provides an important basis for the interpretation of similar studies in alopecia areata.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00829.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

The freeze‐fracture technique was used to study acantholytic cells of untreated pemphigus patients and the cells of histocytosis X. On the membranes of acanthocytosis cells, the particles are randomly distributed and lack the typical desmosome organization, while tight and gap junctions are still found. The study of the cells of histocytosis X provided a better understanding of the structure of the Langerhans granule. The paracrystalline organization of the inner face of the disc‐shaped portion does not seem to involve the membranes limiting the granule, but rather to be confined to a periodically arranged, possibly proteic substance contained between t

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00830.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

An electron microscope investigation was performed on cutaneous biopsies from four patients with Darier's disease. Suprabasal lacunae with acantholytic cells were a prominent feature. Basal cells and acantholytic cells showed an increase in tonofilaments. Corps ronds appeared as vacuolated cells.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00831.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00832.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00833.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY