摘要:

Study of 18 patients with biopsy diagnoses of eosinophilic panniculitis revealed diverse paterns of systemic disease, including Wells' syndrome, vasculitis, atopy, and erythema nodosum as well as localized panniculitis. Significant associated diseases included psychiatric illness, 6(drug dependency, 4): atopy. 5 (asthma. 3): malignancies. 5; immune complex vasculitis, 4; thyroid disease, 2: Wells' eosinophilic cellulitis, 2; glomerulonephritis and sarcoidosis, 1 each. The skin lesions varied from urticarial papules and plaqes to purpura, pustules, and ulcerative lesions hut always included a nodular subcutaneous component, frequently as a presenting complaint. Eosinophilic panniculitis is a non‐specific finding that can signify localized disease, such as an insect bite or injection lipophagic granuloma in a drug‐dependent patient, or systemic lymphoma or immune reactive disease. Eosinophilic panniculitis in erythema nodosum is perhaps its most confusing presentat

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00455.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Papulovcsicular light eruption (PVLE) is a distinct clinical and histological subset of polymorphous light eruption, Biopsies from 16 patients with PV1.L: showed prominent epidermal and dermal changes consisting of intercellular edema, papillary dermal edema and a perivascular and interstitial infiltrate in the upper dermis.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00456.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Two new cases of pilomatrix carcinoma are reported. They were studied immunohistochemically for the presence of high and low‐molecular weight cytokeratins, beta‐2‐microglobulin, S‐100 protein, carcinoembryonic antigen, epithelial membrane anligen, blood group isoantigens, and peanut agglutinin binding. Results of these studies were compared with those obtained in immunohistologic analysis of 13 typical pilomatrixomas, and 4 other benign lesions with hair follicle differentiation. An attempt was made to correlate antigine expression with malignant transformation; however, there were no consistent differences between the 2 groups. It would seem that immunocytochemistry is of no assistance in differential diagnosis between benign and malignant hair matrical tumors. Hence, the pathologist must rely on morphological criteria alone to make a diagnosis of pilomatrix ca

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00457.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

One case of the so‐called „Stewart‐Treves syndrome” (STS), appearing on a lymphoedomatous arm complicating radical mastectomy for brest cancer, was characterized electronmicroscopically and immunohistologically, in order to elucidate its disputed (epithelial vs endothelial) histogenesis. Epithelial and endothelial differentiation markers used comprised: antibodies against keratin, vimentin, factor VIII‐related antigen (F VIII‐RA), HLA‐DR antigens and the lectinUlex europeausagglutinin 1 (UEA I). At the ultrastructural level, neoplastic cells were found to contain typical Weibel‐Palade bodies, whereas by immunohistological techniques they proved to be keratin −negative/vimentin+, F VIII‐RA +, UEAI+, HLA‐DR+. These results rule out a possible epithelial differentiation and strongly favour an en

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00458.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

A patient with figurated, erythematous skin lesions which histologically showed eosinophilic spongiosis and an epithelial intercellular staining with IgG, but no acantholysis, developed erythromelanodernia. This case and a review of the pertinent literature indicate that the diagnosis of pemphigus does not seem to he justified even in the presence of eosinophilic spongiosis and epidermal intercellular antibodies, when the clinical signs of this disease and the typical histological feature, i.e., acantholysis, are lacking.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00459.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

We report the case of a 13‐year‐old girl with extraskeletal Ewing's sarcoma involving the skin and subcutaneous tissue of the upper back. The patient underwent wide local excision and right axillary node dissection, and received chemotherapy with vineristine, actinomycin D, and cyclophosphamide. There was no evidence of recurrence or metastasis in eight months of follow up. Light and electron microscopic features were typical for this neoplasm. Tumor cells contained abundant glycogen, but failed to stain for desmin, keratin, neuron‐specific enolase, or S‐100 protein. We discuss the differential diagnosis of extraskeletal Ewing's sarcoma as well as theories of its histo

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00460.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Paget's disease may occur at mammary and extramammary sites. Mammary Paget's disease typically involves the nipple and adjacent skin. Almost all such cases arc associated with an underlying ductal carcinoma of the breast. A case of Paget's disease occurring HI the site of an ectopic breast adjacent to a supernumerary nipple and associated with an underlying intraductal carcinoma is described. A search of the literature revealed no previous report of such cases. Detailed clinical history and histopathologic, histochemical, and follow‐up information on this case arc presented. The literature on mammary and extramammary Paget's disease is reviewe

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00461.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00462.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00463.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1986.tb00464.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY