ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00981.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

In a case of juvenile xanthogranuloma in an early stage, electron microscopic examination revealed membrane activity resulting in complex interdigitations with subsequent transformation into aggregated cytoplasmic vesicles. Similar membrane complexes were encountered in multinucleated giant cells and they may be a result of endocytosis or remnants of cell membranes of fused macrophages. Other findings were “virus‐like inclusions” in histiocytes and giant cells, intracytoplasmic collagen in fibroblasts and “cross‐banded filamentous aggr

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00982.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

We report a case of granulomatous vasculitis of Wegener. Systemic involvement occurred in spite of chemotherapy and concomitantly with the development of immunological disturbances. The differential diagnosis with other angiocentric granulomatoses and the estimation of the risk of extension to internal organs are primordial because of their prognostic importance.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00983.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

The two cases reported in this paper allow the differentiation pagetoid reticulosis from solitary lesions of mycosis on the basis of clinical, histological ultrustructural immunohistochemical and enzyme histochemical studies. The first patient presented with a slowly growing asymptomatic scaly plaque of 30 years duration Histology of the lesion was typical of pagetoid reticulosis. Immunohistochemical studies showed that the abnormal cells present in the cutaneous infiltrate were not T lymphocytes and ultrastructural studies suggested these were of histocytic origin. The second patient presented with a poikilodermatous lesion present for 14 years with the histology of plaque stage mycosis fungoides. Enzyme and immunohistochemistry showed the predominant T cell nature of the cutaneous infiltrate and electron microscopy showed numerous mycosis fungoides cells. In contrast to generalized forms of mycosis fungoides, no peripheral blood monocyte chemotactic defect was found in either case. Both lesions responded to radiotherapy.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00984.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Langerhans cells were detected in squamous, stratified epithelia lining human dermoid cysts. Their presence was assayed by ATPase staining and reactivity with heteroantisera against “Ia‐like” antigens. Transmission electron microscopic; studies demonstrated variations in the numbers of cells showing Birbeck granules in epithelia with different degrees of keratinzation. Indeterminate cells (i.e. lacking granules), were more frequent in epithelia showing combined mucous and keratinizing differentiation. Membrane‐coating‐granules and keratohyalin granules were present in epithelia containing Langerhans cells with clearly identifiable Birbeck granules. Interepithelial mast cells were observed in epithelia with mucous differentiation. A relationship between Langerhans cells and kerutinization was suggested. Such non‐immune functions are compatible with the known macrophage characteristics

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00985.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Smooth muscle is seen in the skin in three locations, the arrectores pilorum muscles, the wall of vessels and the specialized muscles in genital skin (the dartos, vulvar, and rnamillary muscles of the scrotum, labia majora, and the breast, respectively). We report a case of a leiomyosarcoma of the dartos muscle in a 57‐year‐old man. The histological features of this tumor are similar to the previously reported cases of leiomyosareomas of the skin thought to originate in arrectores pilorum muscles and the wall of vess

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00986.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00987.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00988.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1981.tb00989.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY