摘要:

The characteristic histologic change seen at 2 h in the Rumpel‐Leede (Hess) test is, in addition to focal hemorrhage in the upper dermis, a perivascular lymphocyte infiltrate with focal areas of lymphocytic epidermal invasion. The histologic findings, even with the liquefaction degeneration, are similar to those of purpura simplex and indicate that, early in many forms of vasopermeability, the lymphocyte may be a primary inflammatory cel

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00300.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

The problem of cell survival as well as the biochemical and histological effects on skin of low temperature storage in liquid nitrogen has already received attention. However, little is known of the submicroscopic alterations induced by such treatment. Our study shows that rapid or slow freezing, direct or mediate contact with the liquid nitrogen, pretreatment before freezing, type and concentration of cryoprotectants, all have various effects on the fine morphology of epidermal cells. Glycerol is shown as having better cryoprotective activity than DMSO at concentrations of 15% or less. Our data are examined taking into account all available reports on the problem of cryopreservation and the use of cryoprotectants.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00301.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Biopsies from typical lesions of pitted keratolysis from five patients have been investigated by electron microscopy to provide information on colonization and morphology of the microorganisms involved in this disease. A part of the biopsies was inoculated in culture media, and Corynebacteria were selected for further examination. Electron microscopy revealed a great variability in the morphologic feature of bacteria concerning size, shape, capsule, cell wall, cross wall formation, plasma membrane, nucleoplasm, cytoplasmic organelles and constituents including mesosomes, ribosomes, volutin granules, and glycogen particles. The pleomorphism is thought to be due in part to the diversity of preparation techniques used in this study and in part to different growth conditionsin vivoandin vitro.As a consequence the present findings are only partly comparable with previously published data on bacteria involved in skin diseases. Evidence is presented that bacteria inducing pitted keratolysis may be able to destroy keratin by means of hydrolytic enzymatic activity.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00302.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Multiple malignant Spiegler tumors were observed on the scalp of a 67‐year‐old female patient with brachydactyly and racket‐nails affecting all fingers of both hands. The occurrence of similar clinical features in the family of the patient is suggestive of a hereditary disorder. The light and electron microscopical findings are desc

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00303.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

A patient with extensive systemic mastocytosis and the mastocytosis syndrome was studied by light and electron microscopy. Mast cell proliferation was found in the bone marrow, the liver, spleen and lymph node. In addition, the patient had telangiectasia macularis eruptiva perstans and elevated histamine levels.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00304.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Histological investigations were performed in 11 subjects suffering from melanosis naeviformis Becker. Apart from the well‐known epidermal alterations such as basal hyperpigmentation, slight acanthosis and growth of coarse hair, dermal changes were found in each case. The dermis was considerably thickened and contained numerous small and/or large bundles of smooth muscle without relation to cutaneous adnexa. Thus, melanosis naeviformis Becker can be considered an organoid nevus with epidermal, melanocytic and dermal component

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00305.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Two patients with an inflammatory reaction in a red tattoo had histopathologic changes of lichen planus. The lesions demonstrated a lymphocytic bandlike infiltrate, liquefaction degeneration, acanthosis, hypergranulosis, and orthokeratosis and many hyaline bodies. Metal particles were observed in the region of the dermal‐epidermal reaction. This probably is another example of the lichenoid reaction produced by delayed cellular hypersensitivit

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00306.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

A case of febrile ulceronecrotic Mucha‐Habermann's is presented. This disorder is a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA) characterized by the sudden eruption of diffuse coalescent ulcerations associated with high fever. In the present case the disease was preceded by the milder typical form of PLEVA. Histologically a leukocytoclastic vasculitis was seen in addition to the usual lymphocytic perivascular and lichenoid infiltrate. During the course of the disease the patient developed an interstitial pneumonitis which resolved concomitantly with the cutaneous lesions. Adenovirus type II recovered at the height of the illness from the patient's urine may have etiologic implications in the pathogenesis of the diseas

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00307.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

A case of chromomycosis, caused byFonsecaea pedrosoi, was treated with 5‐fluorocytosine. After 18 weeks of treatment the initial lesions had largely resolved, and no evidence of active disease was observed clinically, histologically or from fungal cultures of the biopsy material. Further resolution of the remaining hypertrophic scar was achieved by intralesional injections of triamcinolone acetonide. Minimal side‐effects were encountered during the therapy, and no recurrence during an 18‐month follow‐up period was observed. The results of this study indicate that 5‐fluorocytosine is an effective and relatively safe mode of therapy in chro

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00308.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1979.tb00309.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY