ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Acute management involves triage, well directed investigation and timely surgical intervention when necessary. All are discussed in this review. Cerebral blood flow (CBF) and flow velocity assessment are among the other investigations mentioned. Other topics include paediatric head injury, cerebrospinal fluid (CSF) fistulae, stab wounds and post-traumatic epilepsy.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Areas of current research in the nature and remediation of the long-term sequelae of traumatic brain injury (TBI) are reviewed. Studies identifying features that predict outcome still greatly outnumber those of efficacy of rehabilitation. A growing interest is in acute biochemical change that may exacerbate poor outcome.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

The application of modern investigative techniques in molecular biology, cytogenetics and immunocytochemistry has yielded much new information on central nervous system tumours bothin vitroandin vivo. Although the clinical potential of these findings is yet to be fully realized, preliminary clinical studies based on this new information are now in progress. The mechanisms and consequences of brain damage in head injury have been studied both clinically and experimentally for many years; new investigative techniques focusing on the cellular and subcellular basis of brain damage have provided information which is interesting not only in terms of basic neurobiology but also in the identification of new areas for possible therapeutic intervention.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

An assessment of contemporary techniques for the diagnosis and management of hydrocephalus and brain edema are reviewed. Further refinements in magnetic resonance imaging (MRI) techniques may aid in the selection of patients with normal pressure hydrocephalus (NPH) who respond to shunting.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Surgical disorders of the central nervous system of children differ significantly from those of adults. The management of these disorders requires an integrated multidisciplinary practice of paediatric specialists in an appropriate paediatric environment. An increasing number of neurosurgeons are now restricting themselves to this field resulting in the more effective diagnosis and treatment of children with neurosurgical disorders.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

The search for effective therapy of acute stroke, centres on the two strategies of restoring blood flow before ischaemia causes irreversible infarction, and moderation of the biochemical changes in ischaemic tissue that cause neuronal death. This review concentrates on the role of lactacidosis, calcium ions, free radicals, and excitatory neurotransmitters in the pathogenesis of neuronal death, and on the therapeutic possibilities in acute stroke emerging from studies in animal models.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Cardiac disorders associated with cerebral embolism including cardiac surgery, myocardial infarction, endocarditis and non-valvular atrial fibrillation (NVAF) are reviewed along with methods to detect cardioembolic sources. Warfarin and aspirin are effective in the primary prevention of stroke in NVAF but the relative efficacy remains to be determined.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Further evidence is presented that rheological abnormalities antedate stroke and are not just a consequence of stroke. Whether these abnormalities should be corrected in the acute phase after stroke is still uncertain. Until more data are available haemodilution is not to be recommended in most cases of acute stroke.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID