摘要:

The senior author and his collaborators have long been concerned with the use of analytical chemical techniques – more specifically, experimental approaches and methodologies primarily based on polarography – to study problems of general chemical interest. Currently, electroanalytical approaches are being used in a systematic investigation of chemical phenomena involving biologically significant compounds, where such approaches seem to offer distinct advantages. Attention has been focused on the behavior of nucleic acid components, pyridine coenzymes, and relevant model compounds in solution as well as the electron-transfer interface. Behavior at the interface involves (a) adsorption of original, intermediate, and product species, (b) association in the adsorbed state, (c) mechanisms and kinetics of electron-transfer (redox) processes, and (d) chemical reactions (kinetics and mechanisms) involving reactant, intermediate (free radical, carbanion), and product species preceding, accompanying and following electron-transfer. Solution behavior includes (a) the "shape" of the compounds as reflected in structure, conformation, and association including stacking, (b) intra-and intermolecular association, and (c) orientation of the compound as it approaches the interface.

ISSN:0007-8980    

DOI:10.1080/10408347608542689

出版商:Taylor & Francis Group    

年代:1976

数据来源: Taylor

摘要:

Three decades have elapsed since the first detection of nuclear magnetic resonance (NMR) effects in bulk matter. The intervening period has been rich in rewarding results as the relevant theory has been thought through, the experimental techniques developed, and the applications accumulated. Nevertheless, a review of the current "state of the art" shows that significant progress continues to be made on almost all fronts. Within the last few years new fields of application have been opened by the development of super-conducting solenoids,1-3by the introduction of various spin-decoupling techniques,4,5and by the method of pulse Fourier transform NMR spectroscopy.6-9As these innovations originate mainly from progress in instrumentation, acquisition of the techniques by individual laboratories involves the expenditure of considerable sums of money. A much less expensive, but nonetheless important, development in NMR spectroscopy has been the recent introduction of paramagnetic lanthanide complexes as "chemical shift reagents." The theoretical background, practical aspects, and applications of these reagents form the subject of this review.

ISSN:0007-8980    

DOI:10.1080/10408347608542690

出版商:Taylor & Francis Group    

年代:1976

数据来源: Taylor