ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00115.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00116.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00117.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00118.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

The substantial recurrence rate of colorectal cancer following potentially curative resection has fuelled the search for effective adjuvant therapy. Revious trials using 5‐fluorouracil (5‐FU) as a single agent or in combination chemotherapy regimens have not demonstrated meaningful benefits. an impression reflected in the results of a meta‐analysis encompassing large patient numbers. Newer developments utilizing intraportal chemotherapy and the combination of 5‐FU and levamisole have resulted in lower recurrence rates and improved survival in patients with colon cancer. In advanced disease. the biochemical modulation of 5‐FU by Leucovorin has been shown to prolong survival in some studies. Combined Chemotherapy and radiotherapy or chemotherapy alone have shown promising results in rectal cancer. These developments have now been incorporated into ongoi

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00119.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00120.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

The aim of this study was to assess the value of colonoscopy as a pen‐operative investigation in patients treated for colorectal cancer by surgical excision. Patients (134 male, 83 female) undergoing curative resection for colorectal carcinoma between August 1984 and January 1989 had colonoscopy within 3 months of surgery. Eleven patients (5%) had a synchronous cancer, which was diagnosed by colonoscopy in eight. In six of these eight, the diagnosis was made after surgery and 3 patients needed a second colectomy. However, in 3 patients the synchronous cancer was removed endoscopically without the need for further surgical resection. Most synchronous cancers had an earlier pathological stage than the index tumour. The rate of synchronous cancers was higher in patients with synchronous benign polyps (16%) than in those without polyps (3%).Colonoscopy is clearly justified as a peri‐operative investigation in all patients undergoing potentially curative resection of colorectal cancer. If possible, the examination should be carried out prior to surgery, to guide the extent of resect

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00121.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

In 1988 a survey of New Zealand general surgeons was conducted, by post, on the subject of routine antimicrobial prophylaxis for elective colorectal surgery. Surgeons who gave routine prophylaxis were asked for details of their regimens; those who did not were asked for their reasons.One hundred and seventy‐five questionnaires were distributed and 167 were returned. Of these, 124 came from surgeons with a colorectal practice, and 118 of the 124 surgeons satisfactorily completed the questionnaire. Routine antimicrobial prophylaxis was given by 96.6% (114 of 118).Of the 114 surgeons prescribing prophylaxis, one antimicrobial agent was used by 36.8%, two were employed by 53.5% and three or five were used by the remainder. The most commonly used (74.6%) antimicrobial agents were cephalosporins which were prescribed, alone or in combination with a nitroimidazole. The most frequent duration (46.4%) of antimicrobial administration was a combination of both the peri‐ and postoperative periods.When antimicrobial spectrum, route and duration of administration were all taken into account, 49.1 % (56 of 114) were considered to give satisfactory regimens. Excessively protracted administration was the most frequent reason for unsatisfactory classification.The results of this survey demonstrate serious deficiencies in the practice of antimicrobial prophylaxis in elective colorectal surgery. These should be addressed through a programme of continuing educat

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00122.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Perforation of the gastrointestinal tract by toothpicks is an uncommon but well described occurrence. Five cases treated by the authors over the past 5 years are described. This series emphasizes the fact that plain abdominal and chest radiology is unhelpful in establishing the diagnosis. Risk factors identified are the wearing of dentures and previous abdominal surgery.

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00123.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Fine bore naso‐enteric feeding tubes are commonly used for entet al alimentation. Although regarded as generally safe, complications associated with their use occur. Case reports presented here highlight the potential hazards of these tubes. Pleuropulmonary complications are reviewed and guidelines suggested for the safe insertion of such tube

ISSN:0004-8682    

DOI:10.1111/j.1445-2197.1991.tb00124.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY