摘要:

The relevant literature on cerebrovascular diseases from the Indian subcontinent in the last 35 years has been reviewed. Most of the data available are from retrospective studies carried out in various large urban hospitals. The incidence of stroke reported is less when compared with western figures, which may be a reflection of the population at risk. The incidence of stroke in the young Indians below the age of 40 years is higher compared to other countries, which again may be a statistical aberration or may be due to local aetiological factors. Ischaemic cerebrovascular complications of pregnancy and puerperium occur frequently, but the total picture is probably the same as elsewhere in the world.

ISSN:0251-5350    

DOI:10.1159/000110808

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

A population-based study of multiple sclerosis (MS) was conducted in 2 northern Colorado counties in 1982 to determine MS prevalence, to compare the rates with recent North American surveys and to compare the methods used in these studies. Provisional cases were identified from: the patient rolls of MS service organizations, chart reviews in 2 neurology practices, a survey of physicians and a review of hospital discharge diagnoses. Crude-point prevalence for the 2-county region was 84 per 100,000. The age-adjusted rate was higher than the rate for the region above the 37th parallel projected from data in a 1976 national survey, but was comparable to rates obtained in localized surveys conducted in the northern tier of the country. The methodological results revealed that the highest yield sources were the MS service organizations and the neurology practice chart reviews. MS prevalence surveys which neglect these methods may underestimate MS prevalence by as much as 20–40

ISSN:0251-5350    

DOI:10.1159/000110809

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

A retrospective case-control study of occupational heavy metal exposure was conducted using 66 amyotrophic lateral sclerosis (ALS) patients and 66 age- and sex-matched controls. Cases were ascertained primarily through a neurology support and research clinic. The self-administered questionnaire probed potential exposure to nine heavy metals: aluminum, lead, lead alkyl, magnesium, manganese, mercury, mercury alkyl, nickel and selenium. Using McNemar''s test and a Mantel Haenszel extended analysis, no association was found between heavy metal exposure and the pathogenesis of ALS in this patient population. Demographic factors, fracture history, immunizations, travel and other variables were similar in ALS patients and controls.

ISSN:0251-5350    

DOI:10.1159/000110810

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

Several epidemiological studies of amyotrophic lateral sclerosis have suggested that this neurological disease is uniformly distributed throughout the world. We report here the only study providing data on the incidence of this disease in France. It is based on a retrospective study of the Limoges region (Limousin) which contains only one university department of neurology. The study, conducted from February 1, 1977, to February 1, 1985, was not limited to in- and out-patients seen at this department, as we also contacted other non-hospital doctors who might have examined such patients. The average normal incidence was found to be 0.91 per 100,000 population. The male:female ratio was 1.16:1, and the median age of onset was 65 years. Median survival was 20.7 months.

ISSN:0251-5350    

DOI:10.1159/000110811

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

A total of 23 patients with motor neuron disease (MND), encompassing 17 cases of amyotrophic lateral sclerosis, 4 of progressive muscular atrophy and 2 of progressive bulbar palsy, was diagnosed in Benghazi, north-eastern Libya, between 1980 and 1985. The male to female ratio was 2.3:1. The average incidence of MND was 0.89/100,000 population/year (0.87 when age and sex-adjusted to the Libyan population). Eighteen patients were alive on the prevalence day, September 15, 1985, which provided a prevalence rate of 3.47/100,000 population (3.42 if adjusted). Age-specific incidence rates were highest in the 50- to 59-year-old age group, 8.14/100,000/year for men and 6.10/100,000/year for women. The median age at the time of diagnosis was 51 years, and the median duration for the 5 dead MND patients after the onset of the disease was 30 months. The median survival time for all MND cases combined was 42 months.

ISSN:0251-5350    

DOI:10.1159/000110812

出版商:S. Karger AG    

年代:1986

数据来源: Karger

ISSN:0251-5350    

DOI:10.1159/000110813

出版商:S. Karger AG    

年代:1986

数据来源: Karger

ISSN:0251-5350    

DOI:10.1159/000110814

出版商:S. Karger AG    

年代:1986

数据来源: Karger