ISSN:0251-5350    

DOI:10.1159/000110746

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

This paper introduces a method which was utilized to sort multiple pathologic diagnoses pertaining to brain tumors into clusters of equivalent diagnostic terms for an epidemiological study of brain cancer. The method enabled the medical record abstractors to ascertain cases for the study. It enabled the reviewing pathologist to identify differences between original and reviewed diagnoses. It identified the large range of classification systems of brain tumors used by practicing pathologists as a factor contributing to confusion of data if slide reviews are not incorporated into epidemiological studies, and demonstrated how the use of a cluster classification alleviates this problem.

ISSN:0251-5350    

DOI:10.1159/000110747

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

Rochester, Minnesota, has over many decades the highest reported incidence rates of primary intracranial neoplasms. This occurs in the absence of any readily identifiable risk factors. A case-control study of neuroepithelial tumors has been undertaken utilizing the records-linkage system at the Mayo Clinic. This study failed to yield any significant findings for the factors examined.

ISSN:0251-5350    

DOI:10.1159/000110748

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

The frequency of abnormal findings at neurological examination was analyzed in an unselected sample of elderly people aged 67–87 years. Absent deep tendon reflexes and impairment of proprioceptive sensation rarely occurred in the elderly. Limitation of upward gaze and convergence appear a common finding, especially in the very old. Overall, the presence of cortical disinhibition signs (primitive reflexes and paratonia) did not discriminate well between subjects without CNS disease and demented patients. Only the presence of a prominent and persistent response to the stimulus and the number of cortical disinhibition signs found in the same subject appear useful criteria to distinguish between normality and dementi

ISSN:0251-5350    

DOI:10.1159/000110749

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

Little is known regarding the pathogenetic factors for Alzheimer''s disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65 we did not find any significant clinical heterogeneity. Furthermore, we found no data in the medical history that are predictive for the development of presenile AD but observed a significantly increased frequency of dementia in the families of AD patients in comparison to controls.

ISSN:0251-5350    

DOI:10.1159/000110750

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

Forty-four elementary school children with average or above average intelligence were found to be 1–2 years behind the expected level of reading ability. They were left to proceed in their conventional education program for the next 3 years. Reassessment revealed that 23 children (52%) had attained a normal reading level. 21 (48%) children remained unchanged. They were categorized into the corrective reading disability (CRD) and specific reading disability (SRD) groups, respectively. Clinical evaluation of both groups showed that children with SRD had a significantly higher incidence of: (1) illiteracy of both parents; (2) low sociocultural standard; (3) positive family history of elementary school failure; (4) abnormal optokinetic nystagmus; (5) disturbed homolateral dominance, and (6) immature EEG tracing over the occipital area. These findings could be of value in identifying high risk children for SR

ISSN:0251-5350    

DOI:10.1159/000110751

出版商:S. Karger AG    

年代:1990

数据来源: Karger