摘要:

For patients who are planning to have chemotherapy, radiotherapy or to undergo bilateral oophorectomy, the loss of ovarian function will result in premature ovarian menopause and loss of fertility. Embryo preservation is not an option for single women or married women because delaying treatment for at least 2 months of in-vitro fertilization cycles is inappropriate and may be life-threatening. This study reports on the indications for ovarian tissue cryobanking and the state of the art of this method in preserving fertility in women with iatrogenic premature menopause.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Human papillomavirus testing has been evaluated as an adjunct to cervical cytologic screening. There is a well-established association between high-risk malignant subtypes of human papillomavirus infection and the development of neoplastic change. Although human papillomavirus infection is a necessary condition for malignant transformation, it is not a sufficient condition. Multiple cofactors are necessary for progression to dysplasia and then to invasive cervical cancer. Because of the multifactorial nature of malignant transformation, current methods of human papillomavirus testing do not add sufficient predictive and diagnostic information over that obtained by cytology and colposcopic biopsy to warrant routine clinical use.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Radical surgery has resulted in impressive cure rates in women with locally advanced vulvar carcinoma. Unfortunately, morbidity mostly related to inguinofemoral lymphadenectomy, is common. The present review discusses innovations in the management of vulvar disease with attempts to reduce attendant morbidity.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Health-related quality of life instruments for cancer patients and specifically for gynecologic cancer patients have been developed, validated and applied in clinical trials. More focused investigations of specific symptoms, side-effects and both short- and long-term toxicities are also being pursued. Assessments are now included as part of many cancer treatment trials and some studies are looking at quality of life in survivors. Another area of investigation seeks to define the types of stress and coping mechanisms being used in order to identify predictors of psychologic distress.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

There is much debate about the risks and benefits of tamoxifen, most specifically about the incidence of associated endometrial cancer. Nearly all of the published trials on the subject have been criticized for methodological flaws and various forms of bias, making resolution of this controversy difficult. There is a consensus, however, that tamoxifen results in an increased incidence of both premalignant and malignant lesions of the endometrium. As the indications for tamoxifen continue to broaden, a larger number of women will be subjected to the potential adverse effects of tamoxifen. Many techniques for screening patients on tamoxifen for the development of endometrial abnormalities have been suggested. None of these methods appears to be consistently clinically or cost effective. We have reviewed the literature on endometrial surveillance in tamoxifen treated women with a focus on the larger publications reported within the past year. From this, we have provided what we hope to be safe and cost-effective recommendations for the management of these patients.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

This review focuses on atypical glandular cells of undetermined significance Pap smears, with attention given to the classifications of atypical glandular cells of undetermined significance, the clinical and histopathologic correlation, and recent advances in triage strategies for this entity. The management of atypical glandular cells of undetermined significance Pap smears will emphasize the significance of this finding in terms of diagnosing dysplasia and carcinoma of the lower female genital tract.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

There has been growing interest in the possibility of screening for ovarian cancer. This article addresses papers published following a systematic review of all prospective ovarian cancer screening studies since 1998. In the past year, new markers have been reported and previous strategies have been refined. A randomized controlled trial of ovarian cancer screening has shown a survival benefit in women who developed ovarian cancer in the screened group. Although the results do not justify ovarian cancer screening in the general population, the data support the need for a larger randomized trial powered to assess the impact of screening on mortality.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Use of artificial technologies is increasing within the United States. Unfortunately, data describing the possible effects of ‘superovulation’ and potential risk of subsequent ovarian carcinoma are not well defined. This discussion focuses on current data regarding the potential for increased risk for ovarian carcinoma in patients who have undergone infertility evaluation and subsequent treatments.

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID

ISSN:1040-872X    

出版商:OVID    

年代:2000

数据来源: OVID