ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Physicians who are board-certified in occupational and environmental medicine often have formal training and experience in toxicology, epidemiology, and industrial hygiene, as well as clinical medicine, human physiology, and pathology, and are well suited to be team members in the various phases of risk assessment, communication, and management. Those with several years of experience in the clinical, as well as administrative practice of occupational and environmental medicine, are engaged in the practical application of risk characterization, risk communication, and risk management on an almost daily basis. We propose that the occupational and environmental medicine physician is in a unique position to bridge the communication gap between those professionals who provide various components of the risk assessment process and those who manage those risks in society.

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Modern molecular and cellular biology have provided powerful new approaches to study cancer in the research laboratory, but these techniques have not been used extensively in field studies or in screening of high-risk occupational cohorts. The primary objective of this study was to demonstrate the use of cellular and molecular methods in combination with medical and epidemiologic methods to identify cancer cases, risk factors, and markers in a previously identified and defined cohort of Chinese workers exposed to benzidine. The screening of exposed workers included occupational, medical, and smoking histories to identify exogenous risk factors, a limited physical examination, Papanicolaou (PAP) urinary cytology, measurement of urine pH, quantitative fluorescence image analysis (QFIA) cytology to detect DNA hyperploidy, and quantitative fluorescence to detect expression of a low-grade bladder tumor-associated antigen (p300) by exfoliated urothelial cells and elevated expression of the neu oncogene product (p185). Detailed analysis of the accuracy of epidemiologic data and the adequacy of samples and accuracy of molecular techniques was carried out. Three groups were included in this study: group 1 included 23 bladder cancer cases who had previously been exposed to benzidine and served as two surrogates for late-emerging disease.

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

The health risks, health perceptions, and health claim costs of health hazard appraisal (HHA) responders and nonresponders were compared in a sample of employees of the Adolph Coors brewery. HHA responders had lower levels of risks than nonresponders. Responders also rated themselves in better health than nonresponders. Despite the health advantage, HHA responders were more likely to file health claims in 1989 than nonresponders and also had significantly greater claims costs. Comparing the top 10% most expensive employees in each group, however, nonresponders had greater claims costs than responders. Distribution patterns also differed based on perceived health status. HHA responders who perceived themselves in poor/fair health status tended to cost less than nonresponders of similar health. Responders perceiving themselves in good/excellent health status cost more than nonresponders. The findings support the “worried well” syndrome in healthy HHA responders.

ISSN:0096-1736    

出版商:OVID    

年代:1993

数据来源: OVID