摘要:

An accumulation of granular cells associated with the enamel organ of a developing deciduous, incisor tooth was noted during light microscopy (LM) of serial sections from the right half of a mandible from a stillborn, female infant of 37 weeks gestations. There was a break in continuity of the enamel matrix associated with the focus of granular cells, which appeared to be continuous with, and arise directly from, the cells of the stratum intermedium.The granular cells were very similar histologically to those of a congenital epulis but it is impossible to say whether the lesion would have developed sufficiently to present clinically as an epulis. Less probably, the granular cells might eventually have been associated with the subsequent development of a granular cell ameloblastoma or ameloblastic fibroma. If the lesion does represent an early stage in the formation of a congenital epulis, it would support the odontogenic theory of origin of the granular cells.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00310.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

The present study shows that14C‐arachidonic acid metabolism in gingiva of patients with periodontal disease is mainly via the lipoxygenase pathway. In two pools of gingival tissue homogenates the lipoxygenase products contained 22.65% and 23.38%, while the prostaglandins (PGs), products of the cyclooxygenase pathway, contained only 4.85% and 3.98% of the total radioactivity incubated. 12‐hydroxy‐eicosatetraenoic acid (12‐HETE), a lipoxygenase product, was detected as a major metabolite of arachidonic acid in

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00311.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

The traditional list of etiological factors related to oral squamous cell carcinoma namely, tobacco, alcohol, syphilis, and oral sepsis has been expanded to include iron deficiency, chronic candidosis, and herpes simplex virus. The development of current concepts in these areas is discussed. In evaluating the need for future research, special emphasis is given to the concepts of multifactorial etiology and the role of mutagens. Suggestions for future research are discussed.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00312.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Thrice weekly applications of carcinogen 4‐nitroquinoline N‐oxide to rat oral mucosa, induced focal acantholytic dyskeratosis (FAD) in about 50% of the animals. Mucosa overlying bone (palate and attached buccal gingiva) was the area of predilection. The number of oral foci per affected animal ranged between 1 and 3. Histologically, the experimental FAD foci showed all the characteristic features described for human focal acantholytic dyskeratosis. FAD appeared unrelated to malignancy development. It is suggested that FAD represents an induced epithelial differentiation or maturation defect caused by a variety of stimuli among which are chemical carcinogens. The present experimental model seems suitable for further histo‐ and cytopathogenetic st

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00313.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

The epithelial‐connective tissue interface in an ameloblastic fibroma with dentinoid formation shows four characteristic features: epithelium which is surrounded by a cellular stroma, by a cell‐free zone, by a cell‐free zone consisting of an amorphous hyaline‐like material, and by a dentinoid material. The ultrastructure of these four characteristics resembles stages of the developing tooth. The cellular epithelial‐connective tissue interface corresponds to early development before the “bud cap” stage described by Sisca and Provenza (1972). The cell‐free zone resembles the “bud cap” stage, and the amorphous layer the “intermediate bell” stage, whereas the interface with dentinoid material has all the features of the “late bell” stage, except for t

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00314.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Formalin‐fixed, paraffin‐embedded tissue sections of fifty oral lichen planus lesions including hypertrophic, atrophic and erosive types, were examined by an immunofluorescent technique for the presence of the ABO blood group antigens. The antigen activity in lichen planus lesions was compared with the reactivity of normal human and Rhesus monkey oral mucosa as controls, and the reactivity of adjacent normal epithelium in the same specimen. A difference in the distribution of the blood group substances was observed in the three different types of oral lichen planus. The hypertrophic showed the strongest staining reaction approaching that of the normal, whereas a decrease in quantity of blood group substances was seen in the atrophic, and a tendency to complete loss in the erosive type. There was a marked tendency for loss of staining to be greater in lesions from older patients; this could be related to the greater frequency of atrophic and erosive lesions in the elde

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00315.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Two hundred and one cases of intraoral salivary gland tumors were studied from the files of the School of Pathology, University of the Witwaterstrand and South African Institute for Medical Research. 145 cases (72.5%) were classified as benign, comprising 140 pleomorphic adenomas and 5 monomorphic adenomas. The other 56 cases were classified as malignant or potentially malignant tumors, represented by 21 adenoid cystic carcinomas, 15 adenocarcinomas, 13 mucoepidermoid tumors, 5 carcinoma in pleomorphic adenomas and 2 epidermoid carcinomas. The patients in the malignant/potentially malignant group were significantly older than those in the benign group and a smaller proportion of their tumors were palatal, the difference being statistically significant. The high frequency of pleomorphic adenoma might result from a relatively higher number of black than white patients in this sample.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00316.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Epithelial outgrowths from hamster cheek pouch explants were cultured for 14 days in media containing calcium concentrations of 0.05 mM, 0.075 mM, 0.1 mM, 0.25 mM, 0.75 mM or 1.45 mM (control). Compared with controls, the cultures grown at lower calcium concentrations (0.25–0.75 mM), exhibited higher mitotic indices and an increase in outgrowth size. The mitotic index of cultures at 0.25 mM calcium concentration was 30 ± 2.26, compared to 24 ± 2.24 for controls. Increase in size of the outgrowths was also observed at 0.25 mM calcium concentration compared with those grown in control medium. The epithelial outgrowths grown in control media exhibited cell stratification not observed at lower calcium concentrations. These studies indicate that lower calcium concentration in the media (0.25–0.75 mM) increased epithelial cell proliferation and inhibited keratiniz

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00317.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Books reviewed in this article:The Role of Calcium in Biological Systems, Volume 1. Eds., Anghileri, L. J.&A. M. Tuffet‐Anghiliri, A. M.Viral Infections in Oral Medicine. Eds., J. J. Hooks&G. W. JordanBiocompatibility of Dental Materials. Vol I: characteristics of dental Tissues and Their response to Dental Materials.Eds., D. C. Smith and D. F. WilliamsIllustrated Distionary of Dentistry. Ed., S. Jablons

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00318.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1983.tb00319.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY