摘要:

Abstract.A critical review of the literature was undertaken to determine if there is valid data to support the contention that oral lichen planus represents a disease with significant potential for malignant degeneration. Although there are reports alleging such a relationship, there is insufficient documented evidence to state with any degree of confidence that oral lichen planus, in itself, represents a premalignant state.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1978.tb01879.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Abstract.Of a total of 1,420 odontogenic cysts, 52 (3.3%) were diagnosed as odontogenic keratocysts. Clinical and histological findings in these 52 cysts are reported. Frozen sections of 26 of the keratocysts were incubated to show the following enzyme activities: NADH2‐ and NADPH2‐diaphorase, glucose‐6‐phosphate dehydrogenase, glutamate dehydrogenase, acid phosphatase, leucine aminopeptidase and ATPase. Furthermore, keratinization was studied with the rhodamine B method and lipids with the oil red O, the OTAN and the acid hematein methods. Sections from epidermis, oral mucosa, radicular cysts, residual cysts and follicular cysts served as reference material. The oxidative enzymes showed strong activity in the keratocyst epithelium which contrasted with weak activity in the reference cysts. Acid phosphatase activity was weak in all epithelia except that in keratocysts, which displayed a marked activity. In the fibrous capsule of the keratocyst a high activity of leucine aminopeptidase was recorded. This high activity contrasted with a weak activity in the reference material. The significance of the histochemical results in relation to the aggressive behavior of the keratocyst is di

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1978.tb01880.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Abstract.The calcifying odontogenic cyst is unusual in that it is frequently found in conjunction with the histologic features of a variety of other odontogenic conditions. Two cases are reported, one of which contained areas histologically similar to the ameloblastic fibro‐odontome and also showed condensations of cells in the stroma beneath epithelial strands proliferating from the cyst lining. In both cases the “ghost cells” stained strongly for disulphide groups but only occasional areas were positive for sulphydryl groups. No amyloid or “amyloid‐like” material was detected. As no part of the current name is specific to this lesion it is suggested that the nomenclature should be changed – perhaps to “g

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1978.tb01881.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Abstract.Deposits of apparently solid material were observed in the small salivary ducts in a series of non‐diseased submandibular glands obtained from necropsies evenly divided by sex and adult age. The deposits were of granular or laminated structure. They were of mixed staining, the majority being predominantly eosinophilic. A small number of deposits were essentially wholly hematoxylinophilic and some of these were probably calcified. The prevalence of deposits, expressed as the number per unit sectional area, increased steadily with increasing age but was unrelated to sex. An apparently close correlation between intraductal salivary deposits and foci of obstructive adenitis in the same series of glands was shown to be mainly due to the common influence of age.The deposits probably form by precipitation of salivary glycoprotein, possibly because of parenchymal age changes. They may be related to early salivary lithogenesis but the statistical evidence of this study suggests that they are unlikely to be a major factor in the etiology of focal obstructive adeniti

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1978.tb01882.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Abstract.Epidermoid carcinoma of the lateral border of the tongue can be induced in a standard strain of hamsters, applying DMBA in acetone after traumatizing the area with a root canal broach. Employing the same technique in an inbred strain of hamsters resulted in the more rapid development of carcinomas. The inbred strain should be a useful model for experimental carcinogenesis of tongue.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1978.tb01883.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1978.tb01884.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY