摘要:

Abstract.Gingival hyperplasia was studied in 13 boys with epilepsy living in a state hospital. Boys were selected on the basis of having gingival hyperplasia, having all teeth between cuspids (upper and lower), having no occlusal abnormality and being cooperative. After gingivectomy, regrowth of gingiva was compared around lateral incisors on one side of the mouth having operator‐assisted oral hygiene with that around lateral incisors on the other side of the mouth without operator‐assisted oral hygiene. Regrowth of tissue was documented by precise photogrammetry. Oral hygiene, gingival inflammation and crevicular fluid were monitored. Less inflammation, less crevicular fluid and less regrowth of gingival tissues occurred around teeth subjected to good oral hygiene. Precise periodic photographic documentation of the clinical status of patients during studies such as this is considered very valua

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01752.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Abstract.The first case report of an oral infection due toTorulopsis glabratais presented. This microorganism is a yeast‐like fungus grouped in a similar family to theCandidaspecies. It has been isolated with increasing frequency from the oral cavity but, surprisingly, has not been reported as a pathogen in this site. In other anatomical sites, including the urinary tract, lung and gastrointestinal tract,Torulopsis glabratahas been reported as a pathogen, at times resulting in a fatal outcome. However, there has usually been some modifying factor, e. g. malignancy, cytotoxic drug therapy, diabetes or broad spectrum antibiotics, which caused this marginal pathogen to assume a pathogenic role. No such modifying factors could be elicited in this case.The history of the case including the management is presented. A brief outline of the microbiologic grouping ofTorulopsis glabratais given, as well as the diagnostic test used in its identification. The histopathology is described and the necessity for combining special tests in establishing a positive diagnosis is exemplified, as the histology alone is not pathognomonic of the infectio

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01753.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Abstract.A specific collagenase has been demonstrated in culture fluids of guinea pig bones. Based on the acrylamide gel eleclrophoretic pattern, the mechanism of action of guinea pig bone collagenase appears similar to other known vertebrate collagenases. Two peaks of enzymatic activity were found upon assay of fractions from gel chromatography, corresponding to molecular weights in the range of 137,000 daltons and 29,000 daltons. The enzyme is inhibited by cysteine and EDTA. Alpha2‐macroglobulin is a much stronger inhibitor of the collagenase than alpha1‐antitrypsin. Activation studies suggested the presence of a proenzyme to guinea pig bone collagenase that was converted to an active enzyme by proteases present in the culture fl

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01754.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Abstract.Testosterone‐4‐14C (2430 pmol, 0.48 μM) was incubated aerobically in 67 mM phosphate buffer pH 7.4 with homogenates and minces of salivary glands from male dogs. Extracted radiosteroids were resolved by thin‐layer chromatography on silica gel, removed and quantitated. Substantially higher NAD+‐dependent 17 β‐hydroxy‐C19‐steroid oxidoreductase activity was found in submaxillary gland homogenates than in similar parotid‐gland preparations. Preliminary evidence is presented that the enzyme activity per unit wet weight of the minced submaxillary gland is decreased in the 2‐week male castrate, in the absence of any recognizable histologic changes in the gland. Testosterone metabolism by canine salivary glands is thus oxidative, contrasting with the reductive 17 β‐hydroxysteroid pathway characteristic of androgen‐dependent organs such as the prostate, and is more extensive than in this accessory sex tissue. Our findings suggest that the canine salivary glands are not target organs for

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01755.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Abstract.The verruciform xanthoma, a rare lesion of the oral cavity, was studied by light and electron microscopy. The major cell type associated with the lesion was shown to contain appreciable amounts of lipid and was characterized as a macrophage. It was characteristic of the endothelial cells associated with subepithelial capillaries to exhibit multiple basal laminae. A rather unusual observation was the migration of lipid‐filled cells into the stratum germinativum of the overlying epitheliu

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01756.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Abstract.Multiple external‐internal resorptions are infrequent and are related to a variety of etiological factors. Thorium X (222Ra) is believed to cause the dental resorptive changes observed in two patients who had received a series of injections each containing 8 to 70 μCi of222Ra 25 years previous

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01757.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1976.tb01758.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY