摘要:

Mucins are the principal organic constituents of mucus, the slimy visco‐elastic material that coats all mucosal surfaces. Compelling evidence suggests that they play an integral role in non‐immune protection of the oral cavity. Specific protective functions include: 1) protection against desiccation and environmental insult, 2) lubrication, and 3) antimicrobial effects against potential pathogens. Biosynthesis of mucin is regulated by both intrinsic (“cooperative sequential specificity”) and extrinsic (“structural modulation”) controls. These controls form the basis by which mucin's structure can be modified to meet a dynamically changing biol

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00138.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Two oral lipomas with osseous and chondrous metaplasia respectively are presented. In the literature we were able to find only four similar lesions.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00139.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Four cases of pleomorphic adenomas of parotid glands were fixed by immersion in a mixture of 4% tannic acid and 3% glutaraldehyde followed by OsO4postfixation and heavy metals staining. This clearly visualized the presence of dense amorphous elastic fibers in cellular and myxochondroid areas. The dense amorphous fibers were associated with varying numbers of peripheral filaments which appeared sometimes as bundles of parallel fibrils without intermingled amorphous material. These intermediate‐sized filaments were seen in direct continuity with similar intracellular filaments with or without interposition of basal‐membrane‐like material and/or with extracellular filament‐containing vesicles.It is suggested that these filaments are synthesized intracellularly and released into the extracellular space by neoplastic myoepithelial cells mainly by cytoplasmic vesicle separation.In addition, small round vesicles with a dense core of amorphous material and staining characteristics identical to those of extracellular elastin were frequently seen in the peripheral parts of these myoepithelial‐like cells. It is possible that these dense‐cored vesicles have a secretory function and contain a precursor

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00140.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

The results of this study have demonstrated a significant reduction in the total epithelial thickness of buccal epithelium in patients with iron deficiency anaemia. This reduction in epithelial thickness occurs principally at the expense of the maturation compartment and the pattern of epithelial change is the same in both male and female patients.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00141.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

The aims of the present study were to demonstrate FcR activity of dental periapical granulomas and to correlate the activity with the degree of lymphoreticular cell infiltration. Cryostat sections of 46 out of 51 granulomas adsorbed sheep erythrocytes (E) sensitized with rabbit IgG antibodies (A) (EA). No adsorption occurred using erythrocytes sensitized with F(ab′)2fragments of IgG. IgG and Fc fragments of human or rabbit IgG inhibited the binding of EA, whereas F(ab′)2fragments, human IgA, IgM or albumin did not, indicating the presence of receptors for the Fc region of IgG. Periodate, neutral formaldehyde and phospholipase C abolished the FcR activity whereas neuraminidase had no effect. Comparison of sections binding EA and adjacent sections stained with haematoxylin and eosin showed that EA adhered to areas infiltrated with mononuclear cells. The degree of binding of EA coincided with the density of mononuclear cell infiltration. Point attachements between the tissue sections and the adsorbed EA could be demonstrated by scanning electron microscopy. Sections with no infiltrates did not bind

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00142.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Twenty‐six individuals who had no history of long‐term antibiotic therapy were examined for the prevalence of β‐lactamase producing bacteria in the oral cavity. Samples from a total of 159 normal and diseased periodontal sites, 44 cheek mucosae, 22 tongue dorsa and 22 salivas were studied. Penicillin resistant organisms were recovered from Trypticase soy blood agar plates containing 1 μg/ml or 2 μg/ml Benzylpenicillin. Beta‐lactamase formation by these isolates was determined using a micro‐iodometric assay. Low levels of penicillin resistant organisms were found in all samples. Approximately 10% of the samples yielded β‐lactamase producing strains. Except for a fewVeillonella parvulastrains, all β‐lactamase forming isolates were members of theBacteriodes melaninogenicussubspeciesmelaninogenicus ‐ Bacteroides oralisgroup of organisms. These species can produce severe infections and, therefore, the present findings may be important in the clinical management of oral an

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00143.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Acid soluble basement membrane collagen (ABMC) was prepared by extraction of the anterior lens capsules from bovine calf eyes in 0.5 M acetic acid in the presence of the protease inhibitors leupeptin and pepstatin. Thermal aggregates formed from soluble basement membrane collagen were facilitated by heating (28°C) the collagen solutions in 0.15 M phosphate buffer. The effects of endotoxins derived fromSalmonella MinnesotaR595,Chromobacterium violaceumandRhodopseudomonas viridison the assembly af basement membrane collagen were ascertained by analysis of turbidity curves (340 nm) obtained during aggregationin vitro.All of the endotoxins tested were noted to inhibit the final level of turbidity and to prolong the lag period for thermal assembly. Plotting the increase in turbidity against the logarithm of time or analyzing the turbidity curves as first‐order reaction indicated that what was altered was the rate of assembly of fibrils in collagen treated with endotoxin, rather than the mechanism of assembly of these fibrils. These conclusions are supported by Arrhenius plots of basement membrane aggregationsin vitroin the presence and absence of endotoxi

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00144.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Books reviewed in this article:Regeneration of the Periodontal Attachment in Humans, by Mick R. DragooMonoclonal Antibodies. Hybridomas: A New Dimension in Biological Analyses, eds. Kennett, R. H. McKearn, J. J.&Bechtol, K. B.SEM Atlas of Cells and Tissues, eds. T. Fujita, K. Tanaka&J. TokunagoMolecules to Living Cells, with introductions by Philip C. HanawaltBasic Oral Physiology, R. M. Bradley, ed.Cancer and Chemotherapy.Vol. I, S. T. Crooke&A. W. Prestayko, eds.Ultrastructure of Bone and Joint Diseases.K. Hirohata, K. Morimoto and H. Kimura, eds.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00145.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00146.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY