ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

The diagnosis of holoprosencephaly usually implies a poor prognosis and is often regarded as a contraindication for surgical correction of associated clefts of the lip or palate. Between 1985 and 1991, 4 patients with lobar holoprosencephaly were evaluated and studied with computed tomography or magnetic resonance imaging. All had cleft palate and 3 had paramedian cleft lip; all 4 exhibited some degree of nasal dysplasia. All patients are presently alive, at a mean age of 26.6 ± 2.4 months (mean ± SD). Three of the children showed normal or near normal development, whereas the fourth was severely retarded. Our experience suggests that some children with lobar holoprosencephaly have a highly variable degree of intellectual development and that long-term survival may be expected.

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Six principles of craniofacial surgery were applied to the treatment of 7 consecutive pediatric patients who sustained complex cranioorbital fractures. These principles are (1) accurate assessment of the deformity, (2) early reconstruction, (3) complete exposure of the involved craniofacial skeleton, (4) accurate anatomical reduction of the fracture fragments, (5) use of rigid internal fixation, and (6) autogenous cranial bone grafting. Patient follow-up ranged from 6 to 52 months; evaluation included serial photographs, three-dimensional computed tomographic imaging, and cephalometric analysis. Application of these 6 craniofacial surgical principles provided definitive management in one operation, with optimal anatomical and functional reconstruction, and resulted in no detectable impairment to subsequent craniofacial growth.

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Because of the Iraq/Iran conflict pediatric facial injuries were commonly seen in Iran. A series of 87 facial injuries were isolated from 1,608 patients with different types of facial injuries seen in two university hospitals in Tehran during the previous 6 years (1984–1990). Their ages ranged from 20 months to 13 years. The male-to-female ratio was 16.4:1; the highest incidence was in the lower-third region (63.21%; n = 55), and the highest incidence was in the 8- to 9-year-old age groups. Associated nonfacial injuries, clinical and computed tomographic scan findings for head injuries associated with facial injuries, treatment, and complications are reported.

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Recently, the temporomandibular joint has been reconstructed with a variety of alloplastic materials; however, functional results are often limited, and long-term stability of the reconstruction is questionable. In contrast, costochondral rib grafting with rigid internal fixation and a temporoparietal fascia flap allows complete functional reconstruction of the temporomandibular joint with autogenous tissue. Thirteen joint reconstructions in 11 patients were followed for up to 7 years and stability of the reconstruction was confirmed. The anterior incisal opening improved from a mean of 14 to 31 mm. Normal occlusal relationships were either reestablished or preserved. Joint pain was ameliorated. The preferred reconstruction of the temporomandibular joint is by autogenous tissue for disc and joint replacement. The treatment provides primary therapy in total joint reconstruction where tumor, trauma, or failed prosthetic joint replacement necessitate complete reconstruction.

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Early investigations attempting to determine the exact pathogenesis of premature closure of the cranial sutures were limited by the untoward sequelae caused by surgical procedures in animal models to simulate the development of craniosynostosis. In an attempt to create a model for evaluating the effects of manipulating the craniofacial sutures without the limitations of associated scarring, we conceived an animal prototype dependent on the effects of insulin growth factor-1 on the anterior frontal suture in a Sprague-Dawley rat model. The experimental group received 2 mg of IGF-1 over a 14-day period via a subcutaneously placed osmotic infusion pump, whereas the age-matched control group received no treatment. We present our preliminary histological results describing the effect of IGF-1 on calvarial sutures.

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:1993

数据来源: OVID