摘要:

AbstractAs more surgeons become familiar with the techniques of hepatic resection and the mortality and morbidity decrease, the indications for resection of malignant disease within the liver broadens. The preoperative assessment of malignant liver lesions, as well as the definition of resectability, are outlined. Indications for operative intervention as well as the results obtained are covered. The personal experience of the authors at the Royal Postgraduate Medical School Hepatobiliary Unit, Hammersmith Hospital, in dealing with malignant lesions of the liver is detailed with respect to procedures performed and postoperative morbidity and mortality. Hepatocellular carcinoma, hilar cholangiocarcinoma, and metastatic colon carcinoma are discussed in detail. The authors' experience with each of these diseases is presented.

ISSN:8756-0437    

DOI:10.1002/ssu.2980030102

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

摘要:

AbstractTumours of the small intestine are a relatively unusual group of benign and malignant tumours of both epithelial and supporting tissue origin. Their pathology, associated syndromes, clinical features, diagnosis, and management are discussed.

ISSN:8756-0437    

DOI:10.1002/ssu.2980030103

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

摘要:

AbstractLung cancer is the leading cause of cancer deaths in both men and women in the United States. Treatment depends on the type and stage of lung cancer. For stage I and II cancer, surgery is usually the treatment of choice. Radiation therapy is used in patients who are considered poor risks for surgical resection. Intraoperative brachytherapy is an effective alternative to external irradiation in this group of patients. From 1958 to 1984, 55 patients with non‐small‐cell lung cancer were explored at Memorial Sloan Kettering Cancer Center and found to have surgical stage I or II tumors, which were considered to be unresectable mainly because of severe obstructive pulmonary disease precluding adequate resection. All these patients were treated with intraoperative brachytherapy at the time of the thoracotomy. Forty‐four percent of these patients received in addition external irradiation, mainly to the mediastinum. The overall 5‐year survival calculated by the Kaplan‐Meier Method was 32%, and the local disease‐free survival was 63%. Cox regression multivariant analysis demonstrated that there is a distinct subgroup with a better prognosis based on tumor site and patient's age—ie, patients who were younger than 58 years of age and had right

ISSN:8756-0437    

DOI:10.1002/ssu.2980030104

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

摘要:

AbstractFrom 1958 to 1982, 1,035 radical mastectomies have been performed in our institute in cases of breast cancer. A total of 804 cases have been followed up for 5 years or more after the operation, the follow‐up rate being 100%. Routine radical operations were performed in 695 cases, whereas the other 109 cases were treated with simple mastectomy, modified radical mastectomy, and extended radical mastectomy. The 5‐, 10‐, 15‐, and 20‐year survival rates of these 804 cases were 71.8%, 58.2%, 48.8%, and 41.8%, respectively. According to the tumor‐node‐metastases (TNM) classification, the 5‐, 10‐, 15‐, and 20‐year survival rates for stage I were 85.4%, 77.0%, 58.3%, and 75.0%; for stage II, 72.8%, 57.4%, 53.5%, and 58.8%; and for stage III, 55.3%, 44.7%, 36.5%, a

ISSN:8756-0437    

DOI:10.1002/ssu.2980030105

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

摘要:

AbstractVirtually 100% of patients with nonmetastatic and low‐risk metastatic trophoblastic tumors are now curable by only conventional chemotherapeutic agents such as methotrexate, actinomycin D, or their combination with or without other agents. However, approximately 30% of high‐risk patients with metastatic trophoblastic tumors are resistant to conventional chemotherapy. All of the high‐risk patients resistant to chemotherapy are those with metastatic choriocarcinoma. Thus, the efficacy of multidrug chemotherapy and combination chemotherapy of cisplatin or VP16‐213 with other agents is now being e

ISSN:8756-0437    

DOI:10.1002/ssu.2980030106

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

摘要:

AbstractA discussion of the current role of chemotherapy in the management of ovarian cancer, based on results obtained from studies by Kurume University Hospital and the Japan Society of Obstetrics and Gynecology (JOG) group, is presented. Higher response rates were obtained for epithelial cancer when combinations of cisplatin, adriamycin, and cyclophosphamide were used. However, cancers such as ovarian cancer that form huge tumor masses cannot be cured completely with chemotherapy alone. Therefore, we think that effective combinations of chemotherapy and surgical treatment are the key to improving patients' prognoses.

ISSN:8756-0437    

DOI:10.1002/ssu.2980030107

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

摘要:

AbstractAlthough cervical cancer is the most common malignancy of the gynecologic system, very few tumor markers have been specially prepared for this disease. This article reviews some of the current investigations of those markers, particularly describing TA‐4, a tumor antigen of cervical squamous cell carcinoma, which has currently been widely used in clinical practic

ISSN:8756-0437    

DOI:10.1002/ssu.2980030108

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY

ISSN:8756-0437    

DOI:10.1002/ssu.2980030101

出版商:John Wiley&Sons, Inc.    

年代:1987

数据来源: WILEY