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Creutzfeldt-Jacob Disease: A Comparative Light-Microscopic, Histochemical and Electron-Microscopic Study

 

作者: J. De Reuck,   W. De Coster,   H. vander Eecken,   P. Daneels,  

 

期刊: European Neurology  （Karger Available online 1975）
卷期: Volume 13, issue 2  

页码: 154-166

 

ISSN:0014-3022

 

年代: 1975

 

DOI:10.1159/000114671

 

出版商: S. Karger AG

 

关键词: Creutzfeldt-Jacob disease;Histochemistry;Electron microscopy;Lipofuscin

 

数据来源: Karger

 

摘要:

The morphological and histochemical findings in a brain biopsy of a case of Creutzfeldt-Jacob disease are compared. The histochemical changes in the cytoplasm of the neurons precede the morphological alterations found with the electron microscope. In this way the neuronal enzymatic failure can explain the clinical picture of this disease.

 

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