Katalytische Markierungsverfahren zur Herstellung von131I-markierter o-Iodhippursäure im Produktionsmaßstab
作者:
K. Rockstroh,
A. Teich,
期刊:
Isotopenpraxis Isotopes in Environmental and Health Studies
(Taylor Available online 1987)
卷期:
Volume 23,
issue 11
页码: 411-414
ISSN:0021-1915
年代: 1987
DOI:10.1080/10256018708623862
出版商: Taylor & Francis Group
关键词: hippuric acid;impurities;iodine 131;isotopic exchange;labelling;labelled compounds;radiopharmaceuticals
数据来源: Taylor
摘要:
The process for catalytic radioiodine labelling of o-iodohippuric acid at a 40 GBq level of Nal31I is described. The in vitro stability of this radiopharmaceutical was investigated and different variants are shown for improving radiochemical purity. The described labelling procedure is used in the routine-production process.
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