Action of Caffeine and Theophylline on Staphylococcal Penicillinase Synthesis
作者:
B.G. Charles,
B.D. Rawal,
期刊:
Chemotherapy
(Karger Available online 1977)
卷期:
Volume 23,
issue 6
页码: 452-457
ISSN:0009-3157
年代: 1977
DOI:10.1159/000222014
出版商: S. Karger AG
关键词: Caffeine;Theophylline;Protein synthesis;PeniciUinase;Synergy;Staphylococcus
数据来源: Karger
摘要:
Both caffeine and theophyllme acting in subinhibitory concentrations inhibit the synthesis of peniciUinase in Staphylococcus aureus. Neither of these compounds inactivate the enzyme. Inhibition of peniciUinase synthesis is attributed to the lack of formation of peniciUinase rather than the elimination of the extrachromosomal plasmid.
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