Central Neuroblastic Tumour Associated with Smooth Muscle Fibers
作者:
O. Vuia,
H. Hager,
期刊:
European Neurology
(Karger Available online 1975)
卷期:
Volume 13,
issue 3
页码: 258-272
ISSN:0014-3022
年代: 1975
DOI:10.1159/000114682
出版商: S. Karger AG
关键词: Neuroblastic tumour;Smooth muscle fibres;Medullomyoblastoma;Malignant teratomas;Dense-core vesicles
数据来源: Karger
摘要:
The present paper is a study of a microcystic intraspinal tumour that developed in a 4-year-old child. The histologic examination showed the presence of neuroblastic elements developing next to smooth muscle fibers. The tumour had diffusely invaded the meninges, presenting a marked collagen reaction. Ultrastructurally, the neuroblastic elements exhibited an arrangement proper to the neural tube and the presence of a series of osmiophil neurosecretory dense-core vesicles. The fine structural morphology of the smooth muscle fibers was clearly revealed, the cells containing microfibrils and being delimited by a basement membrane. The muscular fibers were visibly in contact with the blood vessels. These aspects demonstrate that the medullomyoblastoma is a malignant bidermal teratoid tumour of the central nervous system. Dysgenesis of the ectomesenchyma may be considered to stand at the basis of the development of this type of tumour.
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