Development of Breathing Rat-Lung Models for Particulate Deposition Studies
作者:
Amit L. Patra,
Frederick J. Miller,
Judith A. Graham,
期刊:
Instrumentation Science & Technology
(Taylor Available online 1982)
卷期:
Volume 12,
issue 3
页码: 135-149
ISSN:1073-9149
年代: 1982
DOI:10.1080/10739148208543553
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Techniques have been developed for casting both solid and hollow lung models from rat-lung specimens. To make a solid model, an air line at a positive pressure of 25 cm of water was connected to the trachea to air-dry lungs which had been removed surgically from the animal. Using the lost wax technique, a hollow cast of the airways and the nasopharynx was made. A mechanical breathing system, capable of simulating different breathing patterns, was developed.
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