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Development of Breathing Rat-Lung Models for Particulate Deposition Studies

 

作者: Amit L. Patra,   Frederick J. Miller,   Judith A. Graham,  

 

期刊: Instrumentation Science & Technology  (Taylor Available online 1982)
卷期: Volume 12, issue 3  

页码: 135-149

 

ISSN:1073-9149

 

年代: 1982

 

DOI:10.1080/10739148208543553

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Techniques have been developed for casting both solid and hollow lung models from rat-lung specimens. To make a solid model, an air line at a positive pressure of 25 cm of water was connected to the trachea to air-dry lungs which had been removed surgically from the animal. Using the lost wax technique, a hollow cast of the airways and the nasopharynx was made. A mechanical breathing system, capable of simulating different breathing patterns, was developed.

 

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