We have researched the Universe vacuum properties (vacuum self-organization) that is the problem of the cosmological constant. This problem can’t be solved in terms of the current quantum field theory which operates with Higgs and nonperturbative vacuum condensates and takes into account the changes of these condensates during relativistic phase transitions. The problem can’t be completely solved also in terms of the conventional global quantum theory: Wheeler-DeWitt quantum geometrodynamics does not describe the evolution of the Universe in time (relativistic phase transitions in particular). We have investigated this problem in the context of energies density of different vacuum subsystems characteristic scales of which pervaid all energetic scale of the Universe. The transformation of the cosmological constant in dynamical variable is inevitably. The change of vacuum parameters brings to catastrophic consequences for the Universe (the antropic principle). ©2001 American Institute of Physics.