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Oviductal Damage and the Effect of Estradiol

 

作者: Ginter Sotrel,   Kwabena Kyei-Aboagye,   Sati Chattoraj,   Kenneth C. Edelin,  

 

期刊: Gynecologic and Obstetric Investigation  （Karger Available online 1988）
卷期: Volume 26, issue 2  

页码: 145-152

 

ISSN:0378-7346

 

年代: 1988

 

DOI:10.1159/000293686

 

出版商: S. Karger AG

 

关键词: Estradiol;Oviductal damage;Scanning electron microscopy

 

数据来源: Karger

 

摘要:

Predictable and reproducible epithelial damage can be created by prolonged splinting of the oviduct. Splinting is associated with the flattening of the mucosal folds, pressure atrophy and deciliation of the epithelium. To overcome this detrimental effect, a silastic splint releasing 3 μg/day of estradiol has been compared to an inert splint in rabbits. Scanning electron microscopic observations demonstrated a lesser mucosal damage and reciliation with the steroid-releasing splint.

 

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