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Biphasic form of hepatitis A virus infection: a frequent variant in Argentina

 

作者: Hugo Tanno,   Oscar H. Fay,   José A. Rojman,   Jorge Palazzi,  

 

期刊: Liver  (WILEY Available online 1988)
卷期: Volume 8, issue 1  

页码: 53-57

 

ISSN:0106-9543

 

年代: 1988

 

DOI:10.1111/j.1600-0676.1988.tb00967.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Argentina;biphasic hepatitis A;“cholestatic” jaundice;hepatitis A;relapsing viral hepatitis

 

数据来源: WILEY

 

摘要:

ABSTRACT—In a retrospective study, we review here the clinical presentation of patients with the biphasic form of hepatitis A, a variant of viral hepatitis characterised by an increase in ALAT levels after an initial recovery in clinical condition and laboratory tests. Twenty‐one patients were diagnosed as having a biphasic form; they represent about 10% of a selected population of hepatitis A cases. Six patients were asymptomatic. Eleven patients were jaundiced, nine of them showing a “cholestatic” pattern. The second phase of the disease had a more protracted course and displayed higher ALAT levels than the first phase. The total duration of the disease was 120±28 (mean±SD) days, and its course w

 

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