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Thein vivoeffects of four steroids on glucose‐6‐phosphate dehydrogenase activity of c57L/J mouse erythrocytes

 

作者: E. J. Calabrese,   H. M. Horton,   D. A. Leonard,  

 

期刊: Journal of Environmental Science and Health . Part A: Environmental Science and Engineering  （Taylor Available online 1987）
卷期: Volume 22, issue 6  

页码: 563-574

 

ISSN:0360-1226

 

年代: 1987

 

DOI:10.1080/10934528709375371

 

出版商: Taylor & Francis Group

 

关键词: Steroids;Dehydroepiandrosterone;Epiandrosterone;Glucose‐6‐phosphate Dehydrogenase Deficiency;C57L/J Mice;Erythrocytes

 

数据来源: Taylor

 

摘要:

Preliminary dose‐response relationships were established byin vitroincubation of dehydroepiandrosterone (DHEA) and epiandrosterone (EPI) with human blood. DHEA in increasing concentration resulted in 61% to 76% inhibition of erythrocyte G‐6‐PD activity, while EPI in increasing concentration resulted in 69 to 85% inhibition (p = .001).

 

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