Second Interim Report of the Nation-Wide Collaborative Study on the Long-Term Effects of Bromocriptine in the Treatment of Parkinsonian Patients
作者:
Takao Nakanishi,
Makoto Iwata,
Ikuo Goto,
Ichiro Kanazawa,
Hisayuki Kowa,
Tohru Mannen,
Yoshikuni Mizuno,
Hiroshi Nishitani,
Norio Ogawa,
Akira Takahashi,
Kunio Tashiro,
Hideo Tohgi,
Nobuo Yanagisawa,
期刊:
European Neurology
(Karger Available online 1989)
卷期:
Volume 29,
issue 1
页码: 3-8
ISSN:0014-3022
年代: 1989
DOI:10.1159/000116446
出版商: S. Karger AG
关键词: Parkinson’s disease;Levodopa;Bromocriptine;Treatment;Side effects
数据来源: Karger
摘要:
The interim data obtained up to the end of the 2nd year of the nation-wide multicentric cooperative study on the long-term effects of bromocriptine in parkinsonian patients revealed the following results. Firstly, the bromocriptine monotherapy could be continued in about 40% of the patients at the mean maintenance dose of 10.8 mg daily. Secondly, the additional use of bromocriptine in parkinsonian patients already treated with levodopa had a favorable influence on late side effects of levodopa such as on-off phenomenon and dyskinesia. No significant difference has been found so far as to the management of the wearing-off phenomenon between the patients with levodopa alone and those with levodopa and bromocriptine.
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