SummarySexual problems are,par excellence, psychosomatic conditions and none more so than loss of libido. However, I will be dealing with the organic rather than the emotional. My second disclaimer is that I am going to consider more about loss of libido in women than in men, partly because of my background as a gynaecologist and partly because there is considerably more written about loss of libido in women. Libido is complicated and we do not understand much about its origins, even though we are aware of many of the factors which may alter it. I will address some of these factors and look at how we as clinicians should approach the problem of loss or lack of libido when it presents to us.