The Outcome of Pregnancy in Antinuclear Antibody-Positive Women
作者:
Jorma Kiuttu,
Anna-Liisa Hartikainen,
Reino Mäkitalo,
Pekka Ruuska,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1994)
卷期:
Volume 37,
issue 3
页码: 160-163
ISSN:0378-7346
年代: 1994
DOI:10.1159/000292548
出版商: S. Karger AG
关键词: Antinuclear antibodies;Pregnancy
数据来源: Karger
摘要:
The significance of antinuclear antibodies (ANA) was studied in 51 ANA-positive women who had had a total of 170 pregnancies. 60 ANA-negative age-and parity-matched women with a total of 142 pregnancies served as controls. The perinatal mortality rate in the ANA-positive group was 18.6% (8/43), while there were no perinatal deaths in the ANA-negative control group. All the perinatal losses were stillbirths. The rate of spontaneous abortions was low in both groups, 2.0 vs. 3.3%, respectively. The ANA titer, complement-fixing activity and antigenic specificity did not correlate with the outcome of the pregnancy. Two infants of the ANA-positive women (3.9%) had a congenital atrioventricular heart block. In both cases the ANA was of the complement fixing type.
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