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Importance of Virus Passage History on the Growth of Coxsackie B4 in Human Skin Fibroblasts

 

作者: Michelle Miller,   Gerald B. Harriett,   Marion R. Bucens,  

 

期刊: Intervirology  （Karger Available online 1988）
卷期: Volume 29, issue 1  

页码: 57-60

 

ISSN:0300-5526

 

年代: 1988

 

DOI:10.1159/000150029

 

出版商: S. Karger AG

 

关键词: Coxsackie B4;Fibroblasts;Replication;Adaptation

 

数据来源: Karger

 

摘要:

Human skin fibroblasts have previously been reported to display an age-dependent resistance to infection with coxsackie B4 virus. We have shown that the virus will replicate and produce CPE in human skin fibroblasts regardless of the age of the donor of the cells. The passage history of the virus was found to influence the titre of the virus in these cells.

 

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