Binswanger’s Disease: A Review of the Literature and a Personal Contribution
作者:
T. Sacquegna,
S. Guttmann,
S. Giuliani,
R. Agati,
R. Daidone,
A. Morreale,
G. Ambrosetto,
R. Gallassi,
期刊:
European Neurology
(Karger Available online 1989)
卷期:
Volume 29,
issue 2
页码: 20-22
ISSN:0014-3022
年代: 1989
DOI:10.1159/000116460
出版商: S. Karger AG
关键词: Binswanger’s disease;Leuko-araiosis;Stroke;Dementia
数据来源: Karger
摘要:
Binswanger’s disease is the name which has been given to a form of subcortical vascular dementia. These patients have a particular clinical profile which progressively includes strokes, gait disorder, pseudobulbar signs and cognitive impairment suggesting dysfunction of the prefrontal cortex. The radiological pattern of hypodensity of the white matter on CT scan (or an increased MRI signal), albeit much debated, seems to be more closely associated with hypertension, previous strokes and neuropsychological defects. Binswanger’s disease probably represents the end stage of a pathological process in which hypertensive arteriolopathy, demyelination of the centra semiovale and deep infarcts all play a r
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