Effects of Electroconvulsive Therapy on Brain Glucose MetabolismA Preliminary Study
作者:
Nora Volkow,
Suha Bellar,
Nizar Mullani,
Lance Jould,
Stephen Dewey,
期刊:
Convulsive Therapy
(OVID Available online 1988)
卷期:
Volume 4,
issue 3
页码: 199-205
ISSN:0749-8055
年代: 1988
出版商: OVID
关键词: Electroconvulsive therapy;Brain glucose metabolism;Cerebral blood flow;Tomography, emission computed;Depressive disorder
数据来源: OVID
摘要:
We measured15O water uptake and [18F]fluorodeoxyglucose (FDG) uptake in four depressed individuals before electroconvulsive therapy (ECT) and 24 h after completion of a series of six to 11 bilateral ECT treatments. Studies of radioactive uptake were done using positron emission tomography, with FDG as a measure for glucose metabolism and with oxygen-15-labeled water as a measure for cerebral blood flow. The four patients showed decreased uptake of FDG in the frontal cortex after ECT treatment. Two of the three patients in whom15O water was measured showed decreased uptake in the frontal cortex after ECT.
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