首页   按字顺浏览 期刊浏览 卷期浏览 Variability in Sib Pair Genetic Identity
Variability in Sib Pair Genetic Identity

 

作者: B.K. Suarez,   T. Reich,   P.M. Fishman,  

 

期刊: Human Heredity  (Karger Available online 1979)
卷期: Volume 29, issue 1  

页码: 37-41

 

ISSN:0001-5652

 

年代: 1979

 

DOI:10.1159/000153013

 

出版商: S. Karger AG

 

关键词: Sibs;Identity by descent (IBD);Chromosomes;Crossing over

 

数据来源: Karger

 

摘要:

Using a realistic model of meiotic crossing over the variability in full sib genetic identity is estimated by simulating 200 independent pairs of sibs. The standard deviation of the percentage of the autosomal genome identical by descent (IBD) was found to be about 0.056. Simulations of sibships larger than size two revealed that the average within sibship standard deviation is between 0.054 and 0.056, thus indicating that sib pair variability is insensitive to the nonindependence structure present when considering all possible sib pairs contained in a large sibship.

 

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