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Low Plasma Cyclic Nucleotides in Multiple Sclerosis

 

作者: M. Markianos,   C. Sfagos,  

 

期刊: European Neurology  (Karger Available online 1988)
卷期: Volume 28, issue 5  

页码: 252-254

 

ISSN:0014-3022

 

年代: 1988

 

DOI:10.1159/000116278

 

出版商: S. Karger AG

 

关键词: Multiple sclerosis;AMP;plasma cyclic;GMP;plasma cyclic;Disability status scale

 

数据来源: Karger

 

摘要:

The concentrations of cyclic AMP and cyclic GMP were estimated in plasma of 26 patients with definite multiple sclerosis (MS) in relapse, and compared to that of 26 sex- and age-matched healthy controls. MS patients had significantly lower levels of both nucleotides. The levels of c-GMP correlated negatively to the Disability Status Scale score.

 

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