Radiological evidence of a dose-related response to long-term treatment of Paget's disease with human calcitonin
作者:
期刊:
The British Journal of Radiology
(WILEY Available online 1974)
卷期:
Volume 47,
issue 553
页码: 1-8
年代: 1974
DOI:10.1259/0007-1285-47-553-1
出版商: The British Institute of Radiology
数据来源: WILEY
摘要:
AbstractRadiological observations in 28 patients with Paget's disease of bone treated for 10–40 months with synthetic human calcitonin are presented. A method of evaluating and scoring radiological changes was devised. The results suggest that response to treatment is dose-related. No patient on a dose of 0·5 mg twice daily showed evidence of deterioration and five showed improvement. On a dose of 0·5 mg a day, three patients improved and four deteriorated. On 0·5 mg a week, four patients deteriorated and none improved.
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