A circular dichroism study of the effects of a hemolytic toxin fromgymnodinium breve, the Florida red tide organism, on human erythrocyte membranes
作者:
Martin Schwartz,
期刊:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering
(Taylor Available online 1976)
卷期:
Volume 11,
issue 8-9
页码: 573-581
ISSN:0360-1226
年代: 1976
DOI:10.1080/10934527609385796
出版商: Taylor & Francis Group
关键词: Circular Dichroism;Hemolytic toxin;Gymnodinium breve.
数据来源: Taylor
摘要:
G.ymnodinium breve, the Florida red tide organism, was cultured in enriched seawater medium; the toxin was extracted and a hemolytic fraction separated by column chromatography on Sephadex LH‐20–100. The circular dichroism spectra of isolated human erythrocyte membranes incubated with and without the hemolytic toxin were taken. No changes in the membranes due to the toxin were detected, indicating that membrane proteins were not affected. It was shown that the hemolytic toxin was removed from solution by the isolated membranes, indicating that the toxin was binding to the membranes.
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