Nomifensine Maleate in Adult Attention Deficit Disorder
作者:
WALID SHEKIM,
ALEX MASTERSON,
DENNIS CANTWELL,
GREGORY HANNA,
JAMES McCRACKEN,
期刊:
The Journal of Nervous and Mental Disease
(OVID Available online 1989)
卷期:
Volume 177,
issue 5
页码: 296-299
ISSN:0022-3018
年代: 1989
出版商: OVID
数据来源: OVID
摘要:
The authors studied 18 adults (8 men and 10 women) in an open trial of nomifensine maleate for the treatment of attention deficit disorder (ADD). All patients met DSM-III criteria and the Utah criteria for ADD, residual type (RT). Medication effect was measured at week 1 and week 4 of treatment using the Structured Interview for ADD-H Symptoms. Data from week 4 showed that all eight men and seven of the women responded well to nomifensine, showing a significant decrease in ADD with hyperactivity symptoms. Side effects were minimal, consisting of drowsiness, dry mouth, headache, and nausea. One responder (5%) was taken off the medicine after developing an allergic reaction. Results showed that short-term use of nomifensine was relatively free from side effects and was remarkably effective in the treatment of ADD-RT. The authors discussed the implications of the use of nomifensine and related drugs in the treatment of ADD-RT.
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