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Fetal Circulatory Endothelin-1,2 in the Midtrimester

 

作者: Eyed Schiff,   Yawn Zalel,   Steven A. Friedman,   Eliezer Shalev,  

 

期刊: Gynecologic and Obstetric Investigation  （Karger Available online 1993）
卷期: Volume 35, issue 3  

页码: 185-186

 

ISSN:0378-7346

 

年代: 1993

 

DOI:10.1159/000292696

 

出版商: S. Karger AG

 

关键词: Endothelin-1;2;Fetal circulation;Cordocentesis

 

数据来源: Karger

 

摘要:

Umbilical-vein blood from eight fetuses who underwent cordocentesis for rapid karyotyping at 19–22 gestational weeks was tested for immunoreactive endothelin-1,2 by means of radioimmunoassay. Endothelin was detected in the serum of all but one of these fetuses. Levels of endothelin-1,2 ranged from 8.5 to 19.2 fmol/ml (mean 13.4 fmol/ml). We speculate that endothelin in the fetoplacental circulation may play a role in the regulation of fetal hemodynamics in utero.

 

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