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Protein Components of Amyloid-Like Kidney Stones of Chronic Hemodialysis Patients

 

作者: Hisashi Ozasa,   Toshiaki Suzuki,   Kota Takahashi,   Kazuo Ota,  

 

期刊: Nephron  （Karger Available online 1989）
卷期: Volume 53, issue 3  

页码: 257-260

 

ISSN:1660-8151

 

年代: 1989

 

DOI:10.1159/000185754

 

出版商: S. Karger AG

 

关键词: Hemodialysis;Kidney stones;Lysozyme;Serum amyloid P component;β2-Microglobulin;Amyloid

 

数据来源: Karger

 

摘要:

We have examined amyloid-like kidney stones, commonly found in patients on maintenance hemodialysis. Extraction of protein from the stones and Western blot analysis were performed. β2-Microglobulin (β2MG), serum amyloid P component (SAP), lysozyme and PAS-positive substance were identified in the stones. It is suggested that calcium-mediated association of β2MG, lysozyme, SAP and PAS-positive substance may have an important role in the process of the formation of kidney stones in chronic hemodialysis patien

 

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