Uteroferrin: A protein in search of a function
作者:
R. Michael Roberts,
Fuller W. Bazer,
期刊:
BioEssays
(WILEY Available online 1984)
卷期:
Volume 1,
issue 1
页码: 8-11
ISSN:0265-9247
年代: 1984
DOI:10.1002/bies.950010106
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractUteroferrin, a purple‐colored, iron‐containing acid phosphatase, with many of the properties of a lysosomal hydrolase, transports iron from the mother to the conceptus in pregnant pigs. Uteroferrin, however, is but one member of what may be a broad class of iron‐containing phosphatases with unusual spectral properties which result from a novel type of di‐iron active site. The biological function of uteroferrin is unknown. We argue here that the in vivo function of uteroferrin, despite its undoubted ability to act as a potent acid phosphatase, is that of a transplacental iron tran
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