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A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures

 

作者: G.R. Sutherland,   E. Baker,   D.F. Callen,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1988）
卷期: Volume 47, issue 4  

页码: 201-203

 

ISSN:1424-8581

 

年代: 1988

 

DOI:10.1159/000132549

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

Chromosomes prepared from EBV-transformed lymphoblastoid cell lines show an achromatic gap or fragile sitelike lesion at llq23.1. The low spontaneous expression of this lesion is greatly enhanced by BrdU and n-butyric acid. The lesion was expressed homozygously in all 16 cell lines examined. It is suggested that the lesion is a viral chromosome modification site.

 

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